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Kif15-IN-2

🥰Excellent
Catalog No. T11759Cas No. 672926-33-9

Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.

Kif15-IN-2

Kif15-IN-2

🥰Excellent
Purity: 98.17%
Catalog No. T11759Cas No. 672926-33-9
Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$399-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.17%
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Product Introduction

Bioactivity
Description
Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.
In vitro
Kif15-IN-2 (Compound 14) is an inhibitor targeting the mitotic kinase Hs Kif15, with potential activity against proliferative diseases such as cancer, hyperplasia, restenosis, cardiac hypertrophy, immunological disorders, and inflammation[1].
Chemical Properties
Molecular Weight440.48
FormulaC20H20N6O4S
Cas No.672926-33-9
SmilesCC(C)[C@@H](C(=O)Nc1nc(C)c(s1)-c1nnc(C)o1)n1c(=O)[nH]c2ccccc2c1=O
Relative Density.1.409 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 15 mg/mL (34.05 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.54 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2703 mL11.3513 mL22.7025 mL113.5125 mL
5 mM0.4541 mL2.2703 mL4.5405 mL22.7025 mL
10 mM0.2270 mL1.1351 mL2.2703 mL11.3513 mL
20 mM0.1135 mL0.5676 mL1.1351 mL5.6756 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Kif15-IN-2Kif-15-IN-2Kif15IN2Kif15 IN 2KIF15Kif15
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