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Kif15-IN-2

Name: Kif15-IN-2
Brand: TargetMol
SKU: T11759
Price: 399 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11759Cas No. 672926-33-9

Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.

Kif15-IN-2

🥰Excellent

Purity: 98.17%

Catalog No. T11759Cas No. 672926-33-9

Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.

Pack Size	Price	Availability	Quantity
2 mg	$399	In Stock

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Purity:98.17%

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Product Introduction

Bioactivity

Description	Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.
In vitro	Kif15-IN-2 (Compound 14) is an inhibitor targeting the mitotic kinase Hs Kif15, with potential activity against proliferative diseases such as cancer, hyperplasia, restenosis, cardiac hypertrophy, immunological disorders, and inflammation[1].

Chemical Properties

Molecular Weight	440.48
Formula	C₂₀H₂₀N₆O₄S
Cas No.	672926-33-9
Smiles	CC(C)[C@@H](C(=O)Nc1nc(C)c(s1)-c1nnc(C)o1)n1c(=O)[nH]c2ccccc2c1=O
Relative Density.	1.409 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 15 mg/mL (34.05 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2703 mL	11.3513 mL	22.7025 mL	113.5125 mL
5 mM	0.4541 mL	2.2703 mL	4.5405 mL	22.7025 mL
10 mM	0.2270 mL	1.1351 mL	2.2703 mL	11.3513 mL
20 mM	0.1135 mL	0.5676 mL	1.1351 mL	5.6756 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc