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MSX-130

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Catalog No. T4033Cas No. 4051-59-6
Alias MSX 130

MSX-130 is CXCR4 Antagonist.

MSX-130

MSX-130

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Purity: 99.19%
Catalog No. T4033Alias MSX 130Cas No. 4051-59-6
MSX-130 is CXCR4 Antagonist.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$35In StockIn Stock
5 mg$54In StockIn Stock
10 mg$92In StockIn Stock
25 mg$198In StockIn Stock
50 mg$328In StockIn Stock
100 mg$513In StockIn Stock
200 mg$728-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.19%
Appearance:Solid
Color:White
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Product Introduction

MSX-130 AI Summary
MSX-130 has been assessed for its bioactivity through a Competitive Binding Assay to evaluate its binding efficiency to the SDF-1 binding domain of CXCR4 in MDA-MB-231 cells. The compound was tested by measuring its ability to displace biotinylated TN14003 from CXCR4, resulting in an EC50 and IC50 value both greater than 1000.0 nM. These results suggest that MSX-130 exhibits weak or no significant binding affinity and activity in these particular assays..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
MSX-130 is CXCR4 Antagonist.
SynonymsMSX 130
Chemical Properties
Molecular Weight514.62
FormulaC36H26N4
Cas No.4051-59-6
Smilesc1ccc(cc1)-c1nc([nH]c1-c1ccccc1)-c1ccc(cc1)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: Slightly soluble

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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