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CDK9-IN-8

🥰Excellent
Catalog No. T10746Cas No. 2105956-51-0

CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).

CDK9-IN-8

CDK9-IN-8

🥰Excellent
Purity: 99.54%
Catalog No. T10746Cas No. 2105956-51-0
CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).
Pack SizePriceAvailabilityQuantity
1 mg$32In Stock
5 mg$82In Stock
10 mg$118In Stock
25 mg$198In Stock
50 mg$271In Stock
100 mg$357In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.54%
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Product Introduction

Bioactivity
Description
CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).
Targets&IC50
CDK9:12 nM
Chemical Properties
Molecular Weight569.63
FormulaC31H32FN7O3
Cas No.2105956-51-0
SmilesCN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)nc2n1C1CCCC1
Relative Density.1.41 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 5.2 mg/mL (9.13 mM), Sonication and heating to 80℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7555 mL8.7776 mL17.5553 mL87.7763 mL
5 mM0.3511 mL1.7555 mL3.5111 mL17.5553 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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