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Y-29794 Tosylate

Name: Y-29794 Tosylate
Brand: TargetMol
SKU: T35233
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T35233Cas No. 143984-17-2

Alias Y29794 tosylate, Y-29794, Y29794, Y 29794

Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.

Y-29794 Tosylate

🥰Excellent

Purity: 99.86%

Catalog No. T35233Alias Y29794 tosylate, Y-29794, Y29794, Y 29794Cas No. 143984-17-2

Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$30	In Stock	In Stock
5 mg	$58	In Stock	In Stock
10 mg	$83	In Stock	In Stock
25 mg	$137	In Stock	In Stock
50 mg	$247	In Stock	In Stock
100 mg	$368	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$97	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.86%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.
Targets&IC50	PREP:3 nM
In vitro	Y-29794 Tosylate could penetrate into brain to exhibit dose-dependent and long-lasting inhibition[2].
In vivo	Y-29794 Tosylate selectively and competitively inhibited rat brain PPCE in a reversible manner[2]. Y-29794 Tosylate was found to potentiate the effect of TRH on the release of ACh in the rat hippocampus[2].
Synonyms	Y29794 tosylate, Y-29794, Y29794, Y 29794

Chemical Properties

Molecular Weight	590.86
Formula	C₃₀H₄₂N₂O₄S₃
Cas No.	143984-17-2
Smiles	CC(C1=CC=C(C(C2=CC=CS2)=O)C(SCCCCCCCCN(C)C)=N1)C.CC3=CC=C(S(=O)(O)=O)C=C3
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (84.62 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6924 mL	8.4622 mL	16.9245 mL	84.6224 mL
5 mM	0.3385 mL	1.6924 mL	3.3849 mL	16.9245 mL
10 mM	0.1692 mL	0.8462 mL	1.6924 mL	8.4622 mL
20 mM	0.0846 mL	0.4231 mL	0.8462 mL	4.2311 mL
50 mM	0.0338 mL	0.1692 mL	0.3385 mL	1.6924 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc