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Y-29794 Tosylate

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Catalog No. T35233Cas No. 143984-17-2
Alias Y29794 tosylate, Y-29794, Y29794, Y 29794

Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.

Y-29794 Tosylate
Other Forms of Y-29794 Tosylate:

Y-29794 Tosylate

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Purity: 99.86%
Catalog No. T35233Alias Y29794 tosylate, Y-29794, Y29794, Y 29794Cas No. 143984-17-2
Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$48In StockIn Stock
2 mg$68In StockIn Stock
5 mg$97In StockIn Stock
10 mg$139In StockIn Stock
25 mg$229In StockIn Stock
50 mg$412In StockIn Stock
100 mg$613In StockIn Stock
500 mg$1,320BackorderBackorder
1 mL x 10 mM (in DMSO)$162In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.86%
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Product Introduction

Bioactivity
Description
Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.
Targets&IC50
PREP:3 nM
In vitro
Y-29794 Tosylate could penetrate into brain to exhibit dose-dependent and long-lasting inhibition[2].
In vivo
Y-29794 Tosylate selectively and competitively inhibited rat brain PPCE in a reversible manner[2]. Y-29794 Tosylate was found to potentiate the effect of TRH on the release of ACh in the rat hippocampus[2].
SynonymsY29794 tosylate, Y-29794, Y29794, Y 29794
Chemical Properties
Molecular Weight590.86
FormulaC30H42N2O4S3
Cas No.143984-17-2
SmilesCC(C1=CC=C(C(C2=CC=CS2)=O)C(SCCCCCCCCN(C)C)=N1)C.CC3=CC=C(S(=O)(O)=O)C=C3
Relative Density.1.31g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (84.62 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6924 mL8.4622 mL16.9245 mL84.6224 mL
5 mM0.3385 mL1.6924 mL3.3849 mL16.9245 mL
10 mM0.1692 mL0.8462 mL1.6924 mL8.4622 mL
20 mM0.0846 mL0.4231 mL0.8462 mL4.2311 mL
50 mM0.0338 mL0.1692 mL0.3385 mL1.6924 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

Y-29794 TosylateY29794 TosylateY 29794 TosylateProlylEndopeptidase(PREP)ProlylEndopeptidaseProlyl Endopeptidase (PREP)Prolyl Endopeptidaseprolyl endopeptidasePREP
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