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Trans-Anethole

Name: Trans-Anethole
Brand: TargetMol
SKU: T0762
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0762Cas No. 4180-23-8

Alias 4-Propenylanisole, (E)-Anethole

Trans-Anethole ((E)-Anethole) , an organic compound, is widely served as a condiment substance. It is a derivative of phenylpropene, a type of aromatic compound that exists widely in essential oils.

Trans-Anethole

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Purity: 98.73%

Catalog No. T0762Alias 4-Propenylanisole, (E)-AnetholeCas No. 4180-23-8

Trans-Anethole ((E)-Anethole) , an organic compound, is widely served as a condiment substance. It is a derivative of phenylpropene, a type of aromatic compound that exists widely in essential oils.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 g	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.73%

Appearance:Liquid

Color:Transparent

Resource Download

COA HNMR GC LCMS

Product Introduction

Trans-Anethole AI Summary

Trans-Anethole demonstrates a broad spectrum of bioactivities, including antimicrobial, antifungal, herbicidal, nematicidal, and transporter modulatory effects. It exhibits significant antimicrobial activity with a MIC of >800.0 ug/mL against Staphylococcus aureus, Pseudomonas aeruginosa, Enterobacter aerogenes, Penicillium chrysogenum, and Propionibacterium acnes, whereas lower MIC values are observed against Pityrosporum ovale (100.0 ug/mL), Brevibacterium ammoniagenes, Streptococcus mutans, Escherichia coli, Saccharomyces cerevisiae, and Candida utilis (200.0 ug/mL), and Bacillus subtilis (400.0 ug/mL). Trans-Anethole shows potent herbicidal activity, with a 95.0% to 100.0% inhibition of velvetleaf seed germination at concentrations of 5 mM, 2.5 mM, and 1 mM, respectively. It has a MIC of 200.0 ug/mL against Saccharomyces cerevisiae, Candida albicans, and Pityrosporum ovale and demonstrates antifungal efficacy against Zygosaccharomyces bailii, with the most effective inhibition at pH 3 (MIC = 100.0 ug/mL) and reduced efficacy at pH 9 (MIC = 1600.0 ug/mL). The compound also affects nematicidal activity against Meloidogyne incognita J2 larvae, with EC50 values of 124.0 ug/mL at 96 hours, 140.0 ug/mL at 48 hours, and 170.0 ug/mL at 24 hours. Additionally, Trans-Anethole inhibits Human Jumonji Domain Containing 2E (JMJD2E) with a potency of 35481.3 nM and Aldehyde Dehydrogenase 1 (ALDH1A1) with a potency of 39810.7 nM. Further, it modulates transport processes, showing 89.5% inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells and 124.13% in OATP1B3-transfected CHO cells at 10 uM. The compound also displays antihelmintic activity against Haemonchus contortus, with IC50 values of 4,650,000.0 nM against the egg stage and 14,230,000.0 nM against the larval stage. Lastly, it has bioactivity related to drug excretion in larvae of Spodoptera litura and Trichoplusia ni, indicating a diverse range of potential applications..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Trans-Anethole ((E)-Anethole) , an organic compound, is widely served as a condiment substance. It is a derivative of phenylpropene, a type of aromatic compound that exists widely in essential oils.
Synonyms	4-Propenylanisole, (E)-Anethole

Chemical Properties

Molecular Weight	148.20
Formula	C₁₀H₁₂O
Cas No.	4180-23-8
Smiles	COc1ccc(C=CC)cc1
Relative Density.	Ca. 0.988 g/cm3. Temperature:20 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 32.50 mg/mL (219.30 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2.00 mg/mL (13.50 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.7476 mL	33.7382 mL	67.4764 mL	337.3819 mL
5 mM	1.3495 mL	6.7476 mL	13.4953 mL	67.4764 mL
10 mM	0.6748 mL	3.3738 mL	6.7476 mL	33.7382 mL
20 mM	0.3374 mL	1.6869 mL	3.3738 mL	16.8691 mL
50 mM	0.1350 mL	0.6748 mL	1.3495 mL	6.7476 mL
100 mM	0.0675 mL	0.3374 mL	0.6748 mL	3.3738 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc