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2-Arachidonoylglycerol

Name: 2-Arachidonoylglycerol
Brand: TargetMol
SKU: T14011
Rating: 4.5 (1 reviews)

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Catalog No. T14011Cas No. 53847-30-6

2-Arachidonoylglycerol activates neuronal cannabinoid receptors as a full agonist, and prevents the induction of long-term potentiation at CA3–CA1 synapses.

2-Arachidonoylglycerol

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Catalog No. T14011Cas No. 53847-30-6

2-Arachidonoylglycerol activates neuronal cannabinoid receptors as a full agonist, and prevents the induction of long-term potentiation at CA3–CA1 synapses.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg (26.4 mM * 100 μL in Acetonitrile)	$118	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:95% (as a 9:1 mixture of the 2-AG and 1-AG)

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Product Introduction

Bioactivity

Description	2-Arachidonoylglycerol activates neuronal cannabinoid receptors as a full agonist, and prevents the induction of long-term potentiation at CA3–CA1 synapses.
Targets&IC50	CB1:0.8 μM
In vitro	2-Arachidonylglycerol (2-AG), a cannabinoid ligand obtained from intestinal tissue, functions as a full agonist in activating neuronal cannabinoid receptors. It impedes the development of long-term potentiation at CA3-CA1 synapses and, by binding to cannabinoid receptors, produces effects characteristic of cannabinoid drugs[1].

Chemical Properties

Molecular Weight	378.55
Formula	C₂₃H₃₈O₄
Cas No.	53847-30-6
Smiles	O(C(CO)CO)C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O
Relative Density.	0.992 g/cm3

Storage & Solubility Information

Storage

store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mg/mL (26.42 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6417 mL	13.2083 mL	26.4166 mL	132.0829 mL
5 mM	0.5283 mL	2.6417 mL	5.2833 mL	26.4166 mL
10 mM	0.2642 mL	1.3208 mL	2.6417 mL	13.2083 mL
20 mM	0.1321 mL	0.6604 mL	1.3208 mL	6.6041 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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