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2',3',5'-triacetyl-5-Azacytidine

🥰Excellent
Catalog No. T7840Cas No. 10302-78-0
Alias Nsc291930

2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.

2',3',5'-triacetyl-5-Azacytidine

2',3',5'-triacetyl-5-Azacytidine

🥰Excellent
Purity: 98.34%
Catalog No. T7840Alias Nsc291930Cas No. 10302-78-0
2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$34In StockIn Stock
5 mg$48In StockIn Stock
10 mg$73In StockIn Stock
25 mg$131In StockIn Stock
50 mg$197In StockIn Stock
100 mg$296In StockIn Stock
200 mg$428In StockIn Stock
1 mL x 10 mM (in DMSO)$58In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.34%
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Product Introduction

Bioactivity
Description
2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.
SynonymsNsc291930
Chemical Properties
Molecular Weight370.31
FormulaC14H18N4O8
Cas No.10302-78-0
SmilesCC(=O)OC[C@H]1O[C@H]([C@H](OC(C)=O)[C@@H]1OC(C)=O)n1cnc(N)nc1=O
Relative Density.1.60 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mg/mL (27 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7004 mL13.5022 mL27.0044 mL135.0220 mL
5 mM0.5401 mL2.7004 mL5.4009 mL27.0044 mL
10 mM0.2700 mL1.3502 mL2.7004 mL13.5022 mL
20 mM0.1350 mL0.6751 mL1.3502 mL6.7511 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

prodrugInhibitorinhibitDNMTsDNAMethyltransferaseDNA MTasesDNA Methyltransferase5-Azacytidine2',3',5'-triacetyl-5-Azacytidine2',3',5'triacetyl5Azacytidine2',3',5' triacetyl 5 Azacytidine
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