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Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cells

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $100 | - | In Stock | |
| 5 mg | $242 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $347 | - | In Stock |
| Description | Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cells |
| Targets&IC50 | NF-κB:29.34 μM, NF-κB:25.12 μM (in SK-Hep1 cell) |
| In vitro | Ginsenoside Rg6 may inhibit the proliferation and induce apoptosis of human lymphoma JK cells through mitochondrial dysfunction and increased Bax expression and decreased Bcl-2 expression. In addition, ginsenoside Rg6 can also inhibit the transcriptional activity of NF-κB induced by TNF-α in SK-Hep1 cells with IC50 of 25uM. |
| Molecular Weight | 767 |
| Formula | C42H70O12 |
| Cas No. | 147419-93-0 |
| Smiles | [H][C@@]12[C@H](CC[C@@]1(C)[C@]1(C)C[C@H](O[C@]3([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O[C@]3([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@]3([H])C(C)(C)[C@@H](O)CC[C@]3(C)[C@@]1([H])C[C@H]2O)C(=C)CCC=C(C)C |
| Relative Density. | 1.27 g/cm3 (Predicted) |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (130.38 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (5.22 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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