Shopping Cart

Your shopping cart is currently empty

Acetoacetic acid sodium salt

Name: Acetoacetic acid sodium salt
Brand: TargetMol
SKU: T13528
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T13528Cas No. 623-58-5

Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes.

Acetoacetic acid sodium salt

Copy Product Info

😃Good

Catalog No. T13528Cas No. 623-58-5

Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$41	In Stock	In Stock
2 mg	$59	In Stock	In Stock
5 mg	$97	In Stock	In Stock
10 mg	$147	In Stock	In Stock
25 mg	$240	In Stock	In Stock
50 mg	$360	In Stock	In Stock
100 mg	$535	In Stock	In Stock
500 mg	$1,160	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:≥98%

Appearance:Solid

Color:White

Resource Download

COA HNMR

Product Introduction

Bioactivity

Description

Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes.

In vitro

Acetoacetic acid sodium salt triggers oxidative stress, thereby impeding very-low-density lipoprotein (VLDL) assembly in bovine hepatocytes. This compound, at concentrations of 0.6, 2.4, and 4.8 mM, increases malondialdehyde (MDA) content in the high-dose group (GH), diminishes mRNA levels of Mn-SOD, Cu/Zn SOD, and glutathione peroxidase (GSH-Px) across all groups, and reduces catalase (CAT) mRNA expression in the medial-dose (GM) and GH groups. Furthermore, it suppresses mRNA expression of apolipoprotein B100 (ApoB100), apolipoprotein E (ApoE), and the low-density lipoprotein receptor (LDLR), leading to reduced VLDL assembly and heightened triglyceride (TG) accumulation in bovine hepatocytes.

Chemical Properties

Molecular Weight	124.07
Formula	C₄H₅NaO₃
Cas No.	623-58-5
Smiles	CC(=O)CC(=O)[O-].[Na+]
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 101 mg/mL (814.06 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	8.0600 mL	40.2998 mL	80.5997 mL	402.9983 mL
5 mM	1.6120 mL	8.0600 mL	16.1199 mL	80.5997 mL
10 mM	0.8060 mL	4.0300 mL	8.0600 mL	40.2998 mL
20 mM	0.4030 mL	2.0150 mL	4.0300 mL	20.1499 mL
50 mM	0.1612 mL	0.8060 mL	1.6120 mL	8.0600 mL
100 mM	0.0806 mL	0.4030 mL	0.8060 mL	4.0300 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc