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CDFI

Name: CDFI
Brand: TargetMol
SKU: T82761
Price: 143 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T82761Cas No. 1199797-92-6

CDFI is a lipid II flipase (MurJ) inhibitor that inhibits methicillin-resistant Staphylococcus aureus (MRSA) cell wall biosynthesis, used in the study of MRSA infections.

CDFI

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Purity: 99.86%

Catalog No. T82761Cas No. 1199797-92-6

CDFI is a lipid II flipase (MurJ) inhibitor that inhibits methicillin-resistant Staphylococcus aureus (MRSA) cell wall biosynthesis, used in the study of MRSA infections.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$143	In Stock	In Stock
5 mg	$359	In Stock	In Stock
10 mg	$579	In Stock	In Stock
25 mg	$1,160	-	In Stock
50 mg	$1,560	-	In Stock
100 mg	$2,080	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.86%

Resource Download

COA HPLC HNMR FNMR

Product Introduction

Bioactivity

Description	CDFI is a lipid II flipase (MurJ) inhibitor that inhibits methicillin-resistant Staphylococcus aureus (MRSA) cell wall biosynthesis, used in the study of MRSA infections.
In vitro	CDFI is a novel anti-infective agent targeting MRSA cell wall biosynthesis. [1]

Chemical Properties

Molecular Weight	446.99
Formula	C₂₈H₂₈ClFN₂
Cas No.	1199797-92-6
Smiles	FC=1C=CC=2NC(C=3C=CC=CC3Cl)=C(C2C1)C4CCN(CC=5C=CC=C(C5C)C)CC4

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (178.97 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (7.38 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2372 mL	11.1859 mL	22.3719 mL	111.8593 mL
5 mM	0.4474 mL	2.2372 mL	4.4744 mL	22.3719 mL
10 mM	0.2237 mL	1.1186 mL	2.2372 mL	11.1859 mL
20 mM	0.1119 mL	0.5593 mL	1.1186 mL	5.5930 mL
50 mM	0.0447 mL	0.2237 mL	0.4474 mL	2.2372 mL
100 mM	0.0224 mL	0.1119 mL	0.2237 mL	1.1186 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc