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CID5721353

Name: CID5721353
Brand: TargetMol
SKU: T3940
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3940Cas No. 301356-95-6

Alias BCL6 inhibitor

CID5721353 (BCL6 inhibitor) is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor) that disrupts BCL6/corepressor complexes in vitro and in vivo, and was shown to bind the critical site within the BTB groove.

CID5721353

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Purity: 98.90%

Catalog No. T3940Alias BCL6 inhibitorCas No. 301356-95-6

Pack Size	Price	Availability
2 mg	$30	In Stock
5 mg	$46	In Stock
10 mg	$76	In Stock
25 mg	$143	In Stock
50 mg	$233	In Stock
100 mg	$349	In Stock
200 mg	$497	In Stock
1 mL x 10 mM (in DMSO)	$48	In Stock

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Batch Information

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Purity:98.90%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	CID5721353 (BCL6 inhibitor) is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor) that disrupts BCL6/corepressor complexes in vitro and in vivo, and was shown to bind the critical site within the BTB groove.
Targets&IC50	Bcl-6:212 μM
Synonyms	BCL6 inhibitor

Chemical Properties

Molecular Weight	457.28
Formula	C₁₅H₉BrN₂O₆S₂
Cas No.	301356-95-6
Smiles	OC(=O)CC(N1C(=S)S\C(C1=O)=C1\C(=O)Nc2ccc(Br)cc12)C(O)=O
Relative Density.	2.06 g/cm3 (Predicted)
Color	Red
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (131.21 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.37 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1868 mL	10.9342 mL	21.8684 mL	109.3422 mL
5 mM	0.4374 mL	2.1868 mL	4.3737 mL	21.8684 mL
10 mM	0.2187 mL	1.0934 mL	2.1868 mL	10.9342 mL
20 mM	0.1093 mL	0.5467 mL	1.0934 mL	5.4671 mL
50 mM	0.0437 mL	0.2187 mL	0.4374 mL	2.1868 mL
100 mM	0.0219 mL	0.1093 mL	0.2187 mL	1.0934 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc