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CAY 10465

Name: CAY 10465
Brand: TargetMol
SKU: T4607
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T4607Cas No. 688348-33-6

Alias CAY10465 Exclusive, CAY10465

CAY 10465 is a selective and high-affinity AhR agonist with a Ki of 0.2 nM, and it shows no effect on the estrogen receptor (Ki >100000 nM).

CAY 10465

🥰Excellent

Purity: 98.80%

Catalog No. T4607Alias CAY10465 Exclusive, CAY10465Cas No. 688348-33-6

CAY 10465 is a selective and high-affinity AhR agonist with a Ki of 0.2 nM, and it shows no effect on the estrogen receptor (Ki >100000 nM).

Pack Size	Price	Availability
1 mg	$30	In Stock
2 mg	$44	In Stock
5 mg	$70	In Stock
10 mg	$112	In Stock
25 mg	$239	In Stock
50 mg	$453	In Stock
100 mg	$687	In Stock
1 mL x 10 mM (in DMSO)	$78	In Stock

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Batch Information

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Purity:98.80%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	CAY 10465 is a selective and high-affinity AhR agonist with a Ki of 0.2 nM, and it shows no effect on the estrogen receptor (Ki >100000 nM).
Targets&IC50	AhR:0.2 nM(Ki), ERR:>100000 nM(Ki)
Synonyms	CAY10465 Exclusive, CAY10465

Chemical Properties

Molecular Weight	317.13
Formula	C₁₅H₉Cl₂F₃
Cas No.	688348-33-6
Smiles	FC(F)(F)c1ccc(\C=C\c2cc(Cl)cc(Cl)c2)cc1
Relative Density.	1.378 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (315.33 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1533 mL	15.7664 mL	31.5328 mL	157.6640 mL
5 mM	0.6307 mL	3.1533 mL	6.3066 mL	31.5328 mL
10 mM	0.3153 mL	1.5766 mL	3.1533 mL	15.7664 mL
20 mM	0.1577 mL	0.7883 mL	1.5766 mL	7.8832 mL
50 mM	0.0631 mL	0.3153 mL	0.6307 mL	3.1533 mL
100 mM	0.0315 mL	0.1577 mL	0.3153 mL	1.5766 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc