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Dobutamine hydrochloride

Name: Dobutamine hydrochloride
Brand: TargetMol
SKU: T8149
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T8149Cas No. 49745-95-1

Alias Dobutamine (hydrochloride)

Dobutamine hydrochloride (Dobutamine (hydrochloride)) is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects.

Dobutamine hydrochloride

🥰Excellent

Purity: 99.94%

Catalog No. T8149Alias Dobutamine (hydrochloride)Cas No. 49745-95-1

Dobutamine hydrochloride (Dobutamine (hydrochloride)) is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$48	In Stock	In Stock
50 mg	$68	In Stock	In Stock
100 mg	$97	In Stock	In Stock
500 mg	$233	-	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.94%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Dobutamine hydrochloride (Dobutamine (hydrochloride)) is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects.
In vivo	In wildtype mice increasing doses of dobutamine resulted in subsequent increase in the left ventricular function and heart rate acceleration, but significant inotropic, lusitropic, and chronotropic cardiac response was observed only after high doses of dobutamine.
Animal Research	Animal Model:Tgαq*44 mice (heart failure models). Dosage:0.15 mg/kg, 0.5 mg/kg as a low dose, 1.5 mg/kg, 5 mg/kg, 20 mg/kg as a high dose. Administration:Intraperitoneal injection
Synonyms	Dobutamine (hydrochloride)

Chemical Properties

Molecular Weight	337.84
Formula	C₁₈H₂₄ClNO₃
Cas No.	49745-95-1
Smiles	Cl.CC(CCc1ccc(O)cc1)NCCc1ccc(O)c(O)c1
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 20 mg/mL (59.2 mM), Sonication is recommended.

DMSO: 65 mg/mL (192.4 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.92 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9600 mL	14.7999 mL	29.5998 mL	147.9991 mL
5 mM	0.5920 mL	2.9600 mL	5.9200 mL	29.5998 mL
10 mM	0.2960 mL	1.4800 mL	2.9600 mL	14.7999 mL
20 mM	0.1480 mL	0.7400 mL	1.4800 mL	7.4000 mL
50 mM	0.0592 mL	0.2960 mL	0.5920 mL	2.9600 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0296 mL	0.1480 mL	0.2960 mL	1.4800 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc