Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

TC-E 5003

🥰Excellent
Catalog No. T21826Cas No. 17328-16-4
Alias NSC 30176

TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 μM.

TC-E 5003

TC-E 5003

🥰Excellent
Purity: 97.01%
Catalog No. T21826Alias NSC 30176Cas No. 17328-16-4
TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 μM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$39In StockIn Stock
50 mg$64In StockIn Stock
100 mg$97In StockIn Stock
200 mg$143In Stock-
1 mL x 10 mM (in DMSO)$39In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:97.01%
Contact us for more batch information

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity
Description
TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 μM.
Targets&IC50
PRMT1:1.5 μM
In vitro
The GI50 values for TC-E 5003 were 1.97 μM on MCF7a cells and 4.49 μM on LNCaP cells.
SynonymsNSC 30176
Chemical Properties
Molecular Weight401.26
FormulaC16H14Cl2N2O4S
Cas No.17328-16-4
SmilesClCC(=O)Nc1ccc(cc1)S(=O)(=O)c1ccc(NC(=O)CCl)cc1
Relative Density.1.504 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (112.15 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.98 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4921 mL12.4607 mL24.9215 mL124.6075 mL
5 mM0.4984 mL2.4921 mL4.9843 mL24.9215 mL
10 mM0.2492 mL1.2461 mL2.4921 mL12.4607 mL
20 mM0.1246 mL0.6230 mL1.2461 mL6.2304 mL
50 mM0.0498 mL0.2492 mL0.4984 mL2.4921 mL
100 mM0.0249 mL0.1246 mL0.2492 mL1.2461 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TLR4 signalingTC-E-5003TC-E5003TC-E 5003TCE 5003TC E 5003PRMT1NSC-30176NSC30176InhibitorinhibithPRMT1HistoneMethyltransferaseHistone Methyltransferaseanti-inflammatory
Related Tags: buy TC-E 5003 | purchase TC-E 5003 | TC-E 5003 cost | order TC-E 5003 | TC-E 5003 chemical structure | TC-E 5003 in vitro | TC-E 5003 formula | TC-E 5003 molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.