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GSK3β inhibitor II is a GSK3β inhibitor. GSK3β inhibitor II exhibits the research potential of Alzheimer's disease (AD).

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $45 | In Stock | In Stock | |
| 25 mg | $96 | In Stock | In Stock | |
| 50 mg | $163 | In Stock | In Stock | |
| 100 mg | $223 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $30 | In Stock | In Stock |
| Description | GSK3β inhibitor II is a GSK3β inhibitor. GSK3β inhibitor II exhibits the research potential of Alzheimer's disease (AD). |
| In vitro | GSK3 β Inhibitor II exhibits hydrophobic interactions with Ile62, Phe67, Val70, Ala83, and Leu188, ionic interactions with Lys85, and hydrogen bonding interactions with Lys85 and Val135 residues. GSK3 β Inhibitor II forms a hydrogen bond with Val135 [1]. |
| Molecular Weight | 395.22 |
| Formula | C14H10IN3OS |
| Cas No. | 478482-75-6 |
| Smiles | Ic1cccc(CSc2nnc(o2)-c2ccncc2)c1 |
| Relative Density. | 1.79 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 5.5 mg/mL (13.92 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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