Powder: -20°C for 3 years | In solvent: -80°C for 1 year
EMD 527040 hydrochloride is an effective integrin αVβ6 inhibitor. The IC 50 values of EMD 527040 hydrochloride were 6 nM and 1.6 μM to inhibit αVβ6 binding to fibronectin and αVβ6 expression cells to fibronectin, respectively. EMD 527040 hydrochloride shows antifibrotic activity in animal models of biliary fibrosis and is active in vivo.
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Description | EMD 527040 hydrochloride is an effective integrin αVβ6 inhibitor. The IC 50 values of EMD 527040 hydrochloride were 6 nM and 1.6 μM to inhibit αVβ6 binding to fibronectin and αVβ6 expression cells to fibronectin, respectively. EMD 527040 hydrochloride shows antifibrotic activity in animal models of biliary fibrosis and is active in vivo. |
Molecular Weight | 623.96 |
Formula | C29H33Cl3N4O5 |
CAS No. | 2758431-92-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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EMD 527040 hydrochloride 2758431-92-2 EMD-527040 Hydrochloride EMD 527040 Hydrochloride EMD527040 Hydrochloride inhibitor inhibit