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Toxoflavin

Name: Toxoflavin
Brand: TargetMol
SKU: T17142
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T17142Cas No. 84-82-2

Alias Xanthothricin, Toxoflavine, PKF-118-310

Toxoflavin (Xanthothricin) is an antagonist of the transcription factor 4 (TCF4)/β-catenin complex and also inhibits KDM4A.

Toxoflavin

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Purity: 99.7%

Catalog No. T17142Alias Xanthothricin, Toxoflavine, PKF-118-310Cas No. 84-82-2

Toxoflavin (Xanthothricin) is an antagonist of the transcription factor 4 (TCF4)/β-catenin complex and also inhibits KDM4A.

Pack Size	Price	Availability
1 mg	$42	In Stock
5 mg	$91	In Stock
10 mg	$157	In Stock
25 mg	$323	In Stock
50 mg	$488	In Stock
100 mg	$712	In Stock
1 mL x 10 mM (in DMSO)	$97	In Stock

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Batch Information

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Purity:99.7%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Toxoflavin (Xanthothricin) is an antagonist of the transcription factor 4 (TCF4)/β-catenin complex and also inhibits KDM4A.
Synonyms	Xanthothricin, Toxoflavine, PKF-118-310

Chemical Properties

Molecular Weight	193.16
Formula	C₇H₇N₅O₂
Cas No.	84-82-2
Smiles	Cn1ncnc2c1nc(=O)n(C)c2=O
Relative Density.	1.65g/cm3
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (129.43 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.1771 mL	25.8853 mL	51.7706 mL	258.8528 mL
5 mM	1.0354 mL	5.1771 mL	10.3541 mL	51.7706 mL
10 mM	0.5177 mL	2.5885 mL	5.1771 mL	25.8853 mL
20 mM	0.2589 mL	1.2943 mL	2.5885 mL	12.9426 mL
50 mM	0.1035 mL	0.5177 mL	1.0354 mL	5.1771 mL
100 mM	0.0518 mL	0.2589 mL	0.5177 mL	2.5885 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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