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Sucralose

Name: Sucralose
Brand: TargetMol
SKU: T1399
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1399Cas No. 56038-13-2

Alias Trichlorosucrose, E955

Sucralose is a non-nutritive artificial sweetener and sugar substitute that stimulates appetite in rodents by activating a conserved neural fasting response.

Sucralose

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Purity: 99.89%

Catalog No. T1399Alias Trichlorosucrose, E955Cas No. 56038-13-2

Sucralose is a non-nutritive artificial sweetener and sugar substitute that stimulates appetite in rodents by activating a conserved neural fasting response.

Pack Size	Price	Availability	Quantity
5 g	$29	In Stock
10 g	$38	In Stock

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Purity:99.89%

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COA HNMR HPLC

Product Introduction

Bioactivity

Description	Sucralose is a non-nutritive artificial sweetener and sugar substitute that stimulates appetite in rodents by activating a conserved neural fasting response.
In vitro	Using technetium-99m ((99m)Tc) to trace the morphology of erythrocytes in mice, along with the distribution of tissues traced by sodium pertechnetate (Na(99m)TcO(4)) and technetium-99m diethylenetriaminepentaacetate ((99m)Tc-DTPA), the impact of Sucralose on blood components was assessed. The results indicated that the blood components and cellular morphology of erythrocytes remained unchanged.
In vivo	The co-administration of peas and Sucralose to enteroendocrine cells induces higher levels of CCK (cholecystokinin) and GLP-1 (glucagon-like peptide-1) compared to their individual administration.
Synonyms	Trichlorosucrose, E955

Chemical Properties

Molecular Weight	397.63
Formula	C₁₂H₁₉Cl₃O₈
Cas No.	56038-13-2
Smiles	O([C@]1(CCl)O[C@H](CCl)[C@@H](O)[C@@H]1O)[C@H]2O[C@H](CO)[C@H](Cl)[C@H](O)[C@H]2O
Relative Density.	1.69 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 73 mg/mL (183.59 mM), Sonication is recommended.

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 50 mg/mL (125.75 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	2.5149 mL	12.5745 mL	25.1490 mL	125.7450 mL
5 mM	0.5030 mL	2.5149 mL	5.0298 mL	25.1490 mL
10 mM	0.2515 mL	1.2575 mL	2.5149 mL	12.5745 mL
20 mM	0.1257 mL	0.6287 mL	1.2575 mL	6.2873 mL
50 mM	0.0503 mL	0.2515 mL	0.5030 mL	2.5149 mL
100 mM	0.0251 mL	0.1257 mL	0.2515 mL	1.2575 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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