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Sucralose (Synonyms: Trichlorosucrose, E955)

Name: Sucralose
Brand: TargetMol
SKU: T1399
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T1399 Copy Product Info

Purity: 99.89%

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Sucralose is a non-nutritive artificial sweetener and sugar substitute that stimulates appetite in rodents by activating a conserved neural fasting response.

Sucralose

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Catalog No. T1399

Synonyms Trichlorosucrose, E955

Sucralose is a non-nutritive artificial sweetener and sugar substitute that stimulates appetite in rodents by activating a conserved neural fasting response.

Cas No. 56038-13-2

Pack Size	Price	USA Stock	Global Stock	Quantity
5 g	$29	-	In Stock
10 g	$38	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.89%

Appearance:Solid

Color:White to Yellow

Resource Download

COA HNMR HPLC MS

Product Introduction

Bioactivity

Description	Sucralose is a non-nutritive artificial sweetener and sugar substitute that stimulates appetite in rodents by activating a conserved neural fasting response.
In vitro	Using technetium-99m ((99m)Tc) to trace the morphology of erythrocytes in mice, along with the distribution of tissues traced by sodium pertechnetate (Na(99m)TcO(4)) and technetium-99m diethylenetriaminepentaacetate ((99m)Tc-DTPA), the impact of Sucralose on blood components was assessed. The results indicated that the blood components and cellular morphology of erythrocytes remained unchanged.
In vivo	The co-administration of peas and Sucralose to enteroendocrine cells induces higher levels of CCK (cholecystokinin) and GLP-1 (glucagon-like peptide-1) compared to their individual administration.
Synonyms	Trichlorosucrose, E955

Chemical Properties

Molecular Weight	397.63
Formula	C₁₂H₁₉Cl₃O₈
Cas No.	56038-13-2
Smiles	O([C@]1(CCl)O[C@H](CCl)[C@@H](O)[C@@H]1O)[C@H]2O[C@H](CO)[C@H](Cl)[C@H](O)[C@H]2O
Relative Density.	1.69 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 100 mg/mL (251.49 mM), Sonication is recommended.

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 250 mg/mL (628.73 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5149 mL	12.5745 mL	25.1490 mL	125.7450 mL
5 mM	0.5030 mL	2.5149 mL	5.0298 mL	25.1490 mL
10 mM	0.2515 mL	1.2575 mL	2.5149 mL	12.5745 mL
20 mM	0.1257 mL	0.6287 mL	1.2575 mL	6.2873 mL
50 mM	0.0503 mL	0.2515 mL	0.5030 mL	2.5149 mL
100 mM	0.0251 mL	0.1257 mL	0.2515 mL	1.2575 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc