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FLT3-IN-10

🥰Excellent
Catalog No. T9856Cas No. 2088735-51-5
Alias 2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl-

FLT3-IN-10 (2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl-) (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 shows the potential for the treatment of FLT3-mutated acute myeloid leukemia (AML).

FLT3-IN-10

FLT3-IN-10

🥰Excellent
Purity: 99.8%
Catalog No. T9856Alias 2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl-Cas No. 2088735-51-5
FLT3-IN-10 (2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl-) (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 shows the potential for the treatment of FLT3-mutated acute myeloid leukemia (AML).
Pack SizePriceAvailabilityQuantity
2 mg$32In Stock
5 mg$54In Stock
10 mg$93In Stock
25 mg$191In Stock
50 mg$282In Stock
100 mg$401In Stock
200 mg$545In Stock
1 mL x 10 mM (in DMSO)$52In Stock
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Purity:99.8%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
FLT3-IN-10 (2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl-) (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 shows the potential for the treatment of FLT3-mutated acute myeloid leukemia (AML).
Synonyms2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl-
Chemical Properties
Molecular Weight254.26
FormulaC15H11FN2O
Cas No.2088735-51-5
SmilesFc1ccc(cc1)-c1cnc(Nc2ccccc2)o1
Relative Density.1.265 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (216.31 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.9330 mL19.6649 mL39.3298 mL196.6491 mL
5 mM0.7866 mL3.9330 mL7.8660 mL39.3298 mL
10 mM0.3933 mL1.9665 mL3.9330 mL19.6649 mL
20 mM0.1966 mL0.9832 mL1.9665 mL9.8325 mL
50 mM0.0787 mL0.3933 mL0.7866 mL3.9330 mL
100 mM0.0393 mL0.1966 mL0.3933 mL1.9665 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

FLT3-IN-10FLT3
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