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Telratolimod (MEDI9197) is a toll-like receptors 7/8 agonist. It has an antitumor activity.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $175 | In Stock | In Stock | |
| 2 mg | $248 | In Stock | In Stock | |
| 5 mg | $372 | In Stock | In Stock | |
| 10 mg | $556 | In Stock | In Stock | |
| 25 mg | $896 | In Stock | In Stock | |
| 50 mg | $1,220 | Inquiry | Inquiry | |
| 100 mg | $1,650 | Inquiry | Inquiry |
| Description | Telratolimod (MEDI9197) is a toll-like receptors 7/8 agonist. It has an antitumor activity. |
| In vivo | Telratolimod (50 μg) suppresses the tumor volume and more effectively blocks tumor growth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs the survival of mice bearing large tumors [1]. |
| Synonyms | MEDI9197, 3M-052 |
| Molecular Weight | 593.89 |
| Formula | C36H59N5O2 |
| Cas No. | 1359993-59-1 |
| Smiles | CCCCCCCCCCCCCCCCCC(=O)NCCCCOn1c(CCCC)nc2c(N)nc3ccccc3c12 |
| Relative Density. | 1.08 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 1.8 mg/mL (3.03 mM), Sonication is recommended. Ethanol: 12.5 mg/mL (21.05 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO/Ethanol
Ethanol
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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