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Telratolimod

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Catalog No. T17032Cas No. 1359993-59-1
Alias MEDI9197, 3M-052

Telratolimod (MEDI9197) is a toll-like receptors 7/8 agonist. It has an antitumor activity.

Telratolimod

Telratolimod

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Purity: 98.61%
Catalog No. T17032Alias MEDI9197, 3M-052Cas No. 1359993-59-1
Telratolimod (MEDI9197) is a toll-like receptors 7/8 agonist. It has an antitumor activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$175In StockIn Stock
2 mg$248In StockIn Stock
5 mg$372In StockIn Stock
10 mg$556In StockIn Stock
25 mg$896In StockIn Stock
50 mg$1,220InquiryInquiry
100 mg$1,650InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.61%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Telratolimod (MEDI9197) is a toll-like receptors 7/8 agonist. It has an antitumor activity.
In vivo
Telratolimod (50 μg) suppresses the tumor volume and more effectively blocks tumor growth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs the survival of mice bearing large tumors [1].
SynonymsMEDI9197, 3M-052
Chemical Properties
Molecular Weight593.89
FormulaC36H59N5O2
Cas No.1359993-59-1
SmilesCCCCCCCCCCCCCCCCCC(=O)NCCCCOn1c(CCCC)nc2c(N)nc3ccccc3c12
Relative Density.1.08 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 1.8 mg/mL (3.03 mM), Sonication is recommended.
Ethanol: 12.5 mg/mL (21.05 mM), Sonication is recommended.
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM1.6838 mL8.4191 mL16.8381 mL84.1907 mL
Ethanol
1mg5mg10mg50mg
5 mM0.3368 mL1.6838 mL3.3676 mL16.8381 mL
10 mM0.1684 mL0.8419 mL1.6838 mL8.4191 mL
20 mM0.0842 mL0.4210 mL0.8419 mL4.2095 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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