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Quilseconazole Formic acid(1340593-70-5 Free base)

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Catalog No. T16704L
Alias Quilseconazole Formic acid(1340593-70-5 Free base)

Quilseconazole Formic acid is a selective inhibitor of fungal Cyp51 with potent activities against Cryptococcus neoformans and Cryptococcus gattii.

Quilseconazole Formic acid(1340593-70-5 Free base)

Quilseconazole Formic acid(1340593-70-5 Free base)

😃Good
Purity: 99.84%
Catalog No. T16704LAlias Quilseconazole Formic acid(1340593-70-5 Free base)
Quilseconazole Formic acid is a selective inhibitor of fungal Cyp51 with potent activities against Cryptococcus neoformans and Cryptococcus gattii.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$61-In Stock
5 mg$115-In Stock
10 mg$196-In Stock
25 mg$316-In Stock
50 mg$428-In Stock
100 mg$587-In Stock
200 mg$773-In Stock
1 mL x 10 mM (in DMSO)$170-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:99.84%
ee:96.20%
Appearance:Solid
Color:White to Yellow
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Product Introduction

Bioactivity
Description
Quilseconazole Formic acid is a selective inhibitor of fungal Cyp51 with potent activities against Cryptococcus neoformans and Cryptococcus gattii.
SynonymsQuilseconazole Formic acid(1340593-70-5 Free base)
Chemical Properties
Molecular Weight559.39
FormulaC23H16F7N5O4
SmilesFC(F)(C1=CC=C(C2=CC=C(C=C2)OC(F)(F)F)C=N1)[C@@](O)(C3=C(C=C(C=C3)F)F)CN4C=NN=N4.O=C(O)[H]
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (98.32 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7877 mL8.9383 mL17.8766 mL89.3831 mL
5 mM0.3575 mL1.7877 mL3.5753 mL17.8766 mL
10 mM0.1788 mL0.8938 mL1.7877 mL8.9383 mL
20 mM0.0894 mL0.4469 mL0.8938 mL4.4692 mL
50 mM0.0358 mL0.1788 mL0.3575 mL1.7877 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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