Melatonin-d4

Name: Melatonin-d4
Brand: TargetMol
SKU: T11995
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11995Cas No. 66521-38-8

Alias N-Acetyl-5-methoxytryptamine D5, Melatonin D5

Melatonin D5, a deuterium-labeled version of melatonin, is a hormone produced by the pineal gland, known for its role as a selective ATF-6 inhibitor that promotes apoptosis in human hepatoma cells via COX-2 downregulation. Additionally, it activates melatonin receptors and exhibits antioxidative and anti-inflammatory properties.

Melatonin-d4

😃Good

Catalog No. T11995Alias N-Acetyl-5-methoxytryptamine D5, Melatonin D5Cas No. 66521-38-8

Pack Size	Price	Availability	Quantity
1 mg	$246	In Stock
1 mL x 10 mM (in DMSO)	$29	7-10 days

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Product Introduction

Bioactivity

Description	Melatonin D5, a deuterium-labeled version of melatonin, is a hormone produced by the pineal gland, known for its role as a selective ATF-6 inhibitor that promotes apoptosis in human hepatoma cells via COX-2 downregulation. Additionally, it activates melatonin receptors and exhibits antioxidative and anti-inflammatory properties.
Synonyms	N-Acetyl-5-methoxytryptamine D5, Melatonin D5

Chemical Properties

Molecular Weight	236.3
Formula	C₁₃H₁₆N₂O₂
Cas No.	66521-38-8
Smiles	[2H]C([2H])(NC(C)=O)C([2H])([2H])c1c[nH]c2ccc(OC)cc12
Relative Density.	1.196g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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