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TGFβ-IN-5

Name: TGFβ-IN-5
Brand: TargetMol
SKU: T77786
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77786Cas No. 259870-32-1

Alias WAY-641966

TGFβ-IN-5 (WAY-641966) is a potent TGFβ inhibitor with anti-prion activity for the study of fibroproliferative diseases associated with TGF-β signaling.

TGFβ-IN-5

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Purity: 99.62%

Catalog No. T77786Alias WAY-641966Cas No. 259870-32-1

TGFβ-IN-5 (WAY-641966) is a potent TGFβ inhibitor with anti-prion activity for the study of fibroproliferative diseases associated with TGF-β signaling.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$36	-	In Stock
5 mg	$86	-	In Stock
10 mg	$130	-	In Stock
25 mg	$223	-	In Stock
50 mg	$323	-	In Stock
100 mg	$463	-	In Stock
200 mg	$648	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.62%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	TGFβ-IN-5 (WAY-641966) is a potent TGFβ inhibitor with anti-prion activity for the study of fibroproliferative diseases associated with TGF-β signaling.
Synonyms	WAY-641966

Chemical Properties

Molecular Weight	312.37
Formula	C₂₀H₁₆N₄
Cas No.	259870-32-1
Smiles	N=1C=CC(=CC1)CNC=2N=C(N=C3C=CC=CC32)C=4C=CC=CC4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (160.07 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2013 mL	16.0067 mL	32.0133 mL	160.0666 mL
5 mM	0.6403 mL	3.2013 mL	6.4027 mL	32.0133 mL
10 mM	0.3201 mL	1.6007 mL	3.2013 mL	16.0067 mL
20 mM	0.1601 mL	0.8003 mL	1.6007 mL	8.0033 mL
50 mM	0.0640 mL	0.3201 mL	0.6403 mL	3.2013 mL
100 mM	0.0320 mL	0.1601 mL	0.3201 mL	1.6007 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc