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VU590 is a potent and moderately selective inhibitor of extrarenal medullary potassium ROMK (Kir1.1) that also inhibits Kir7.1 and modulates uterine myometrial contractility and melanocortin signalling.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 2 mg | $38 | In Stock | In Stock | |
| 5 mg | $60 | In Stock | In Stock | |
| 10 mg | $98 | In Stock | In Stock | |
| 25 mg | $163 | In Stock | In Stock | |
| 50 mg | $247 | In Stock | In Stock | |
| 100 mg | $372 | - | In Stock |
| Description | VU590 is a potent and moderately selective inhibitor of extrarenal medullary potassium ROMK (Kir1.1) that also inhibits Kir7.1 and modulates uterine myometrial contractility and melanocortin signalling. |
| Targets&IC50 | Kir1.1:290 nM, Kir7.1:8 μM |
| Molecular Weight | 488.53 |
| Formula | C24H32N4O7 |
| Cas No. | 313505-85-0 |
| Smiles | Cl.Cl.[O-][N+](=O)c1ccc(CN2CCOCCOCCN(Cc3ccc(cc3)[N+]([O-])=O)CCOCC2)cc1 |
| Relative Density. | 1.216 g/cm3 (Predicted) |
| Color | Yellow |
| Appearance | Solid |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
| Solubility Information | DMSO: < 20 mg/mL, Sonication is recommended. H2O: 1 mg/mL (2.05 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
H2O
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