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AN3199

Name: AN3199
Brand: TargetMol
SKU: T10316
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T10316Cas No. 1187187-10-5

AN3199 is a selective inhibitor of PDE4 with an IC50 of 94.5 nM.

AN3199

🥰Excellent

Purity: 99.45%

Catalog No. T10316Cas No. 1187187-10-5

AN3199 is a selective inhibitor of PDE4 with an IC50 of 94.5 nM.

Pack Size	Price	Availability
5 mg	$29	In Stock
10 mg	$29	In Stock
25 mg	$41	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.45%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	AN3199 is a selective inhibitor of PDE4 with an IC50 of 94.5 nM.
Targets&IC50	PDE4:94.5 nM (IC50)

Chemical Properties

Molecular Weight	327.14
Formula	C₁₇H₁₈BNO₅
Cas No.	1187187-10-5
Smiles	CCCCOC(=O)c1ccc(Oc2ccc3B(O)OCc3c2)nc1
Relative Density.	1.27 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90.0 mg/mL (275.1 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0568 mL	15.2840 mL	30.5680 mL	152.8398 mL
5 mM	0.6114 mL	3.0568 mL	6.1136 mL	30.5680 mL
10 mM	0.3057 mL	1.5284 mL	3.0568 mL	15.2840 mL
20 mM	0.1528 mL	0.7642 mL	1.5284 mL	7.6420 mL
50 mM	0.0611 mL	0.3057 mL	0.6114 mL	3.0568 mL
100 mM	0.0306 mL	0.1528 mL	0.3057 mL	1.5284 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc