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Brassinin

Name: Brassinin
Brand: TargetMol
SKU: T4373
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4373Cas No. 105748-59-2

Alias BSN

Brassinin (BSN) (BSN) is a phytoalexin isolated from B. campestris that exhibits anticancer, chemopreventative, antiproliferative, and antifungal activities.

Brassinin

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Purity: 97.79%

Catalog No. T4373Alias BSNCas No. 105748-59-2

Brassinin (BSN) (BSN) is a phytoalexin isolated from B. campestris that exhibits anticancer, chemopreventative, antiproliferative, and antifungal activities.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$33	In Stock	In Stock
5 mg	$56	In Stock	In Stock
10 mg	$98	In Stock	In Stock
25 mg	$162	In Stock	In Stock
50 mg	$238	In Stock	In Stock
100 mg	$357	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$58	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:97.79%

Resource Download

COA HNMR HPLC LCMS

Product Introduction

Bioactivity

Description	Brassinin (BSN) (BSN) is a phytoalexin isolated from B. campestris that exhibits anticancer, chemopreventative, antiproliferative, and antifungal activities.
In vitro	In lung cancer cells, brassinin inhibits constitutive and IL-6-inducible STAT3 signaling through modulation of PIAS-3 and SOCS-3.It appears that brassinin induces apoptosis in PC-3 prostate cancer cells via the suppression of PI3K/Akt/mTOR/S6K1 signaling.
In vivo	Brassinin attenuates tumor growth in a xenograft lung cancer mouse model through modulation of E3 SUMO-protein ligase 3 (PIAS-3) and suppressor of cytokine signaling-3 (SOCS-3).
Synonyms	BSN

Chemical Properties

Molecular Weight	236.36
Formula	C₁₁H₁₂N₂S₂
Cas No.	105748-59-2
Smiles	CSC(=S)NCc1c[nH]c2ccccc12
Relative Density.	1.32 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (232.7 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.2308 mL	21.1542 mL	42.3083 mL	211.5417 mL
5 mM	0.8462 mL	4.2308 mL	8.4617 mL	42.3083 mL
10 mM	0.4231 mL	2.1154 mL	4.2308 mL	21.1542 mL
20 mM	0.2115 mL	1.0577 mL	2.1154 mL	10.5771 mL
50 mM	0.0846 mL	0.4231 mL	0.8462 mL	4.2308 mL
100 mM	0.0423 mL	0.2115 mL	0.4231 mL	2.1154 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

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