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Brassinin

Name: Brassinin
Brand: TargetMol
SKU: T4373
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: BSN) Copy Product Info

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Synonyms: BSN

Catalog No. T4373 Copy Product Info

Purity: 97.79%

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Brassinin (BSN) (BSN) is a phytoalexin isolated from B. campestris that exhibits anticancer, chemopreventative, antiproliferative, and antifungal activities.

Cas No. 105748-59-2

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Pack Size	Price	USA Stock	Global Stock
2 mg	$33	In Stock	In Stock
5 mg	$56	In Stock	In Stock
10 mg	$98	In Stock	In Stock
25 mg	$162	In Stock	In Stock
50 mg	$238	In Stock	In Stock
100 mg	$357	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$58	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:97.79%

Appearance:Solid

Color:White

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COA LCMS HNMR HPLC

Product Introduction

Bioactivity

Description	Brassinin (BSN) (BSN) is a phytoalexin isolated from B. campestris that exhibits anticancer, chemopreventative, antiproliferative, and antifungal activities.
In vitro	In lung cancer cells, brassinin inhibits constitutive and IL-6-inducible STAT3 signaling through modulation of PIAS-3 and SOCS-3.It appears that brassinin induces apoptosis in PC-3 prostate cancer cells via the suppression of PI3K/Akt/mTOR/S6K1 signaling.
In vivo	Brassinin attenuates tumor growth in a xenograft lung cancer mouse model through modulation of E3 SUMO-protein ligase 3 (PIAS-3) and suppressor of cytokine signaling-3 (SOCS-3).
Synonyms	BSN

Chemical Properties

Molecular Weight	236.36
Formula	C₁₁H₁₂N₂S₂
Cas No.	105748-59-2
Smiles	CSC(=S)NCc1c[nH]c2ccccc12
Relative Density.	1.32 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 83.33 mg/mL (352.56 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Saline: < 8.33 mg/mL (35.24 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 8.33 mg/mL (35.24 mM), Solution.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.2308 mL	21.1542 mL	42.3083 mL	211.5417 mL
5 mM	0.8462 mL	4.2308 mL	8.4617 mL	42.3083 mL
10 mM	0.4231 mL	2.1154 mL	4.2308 mL	21.1542 mL
20 mM	0.2115 mL	1.0577 mL	2.1154 mL	10.5771 mL
50 mM	0.0846 mL	0.4231 mL	0.8462 mL	4.2308 mL
100 mM	0.0423 mL	0.2115 mL	0.4231 mL	2.1154 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc