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Ruboxistaurin

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Catalog No. T63013Cas No. 169939-94-0

Ruboxistaurin (LY333531) is a selective, orally active PKC beta inhibitor with a Ki value of 2 nM. Ruboxistaurin competitively inhibits PKC beta I (IC50: 4.7 nM) in an ATP-dependent manner. Ruboxistaurin is able to act on PKC beta II (IC50: 5.9 nM).

Ruboxistaurin
Other Forms of Ruboxistaurin:

Ruboxistaurin

😃Good
Catalog No. T63013Cas No. 169939-94-0
Ruboxistaurin (LY333531) is a selective, orally active PKC beta inhibitor with a Ki value of 2 nM. Ruboxistaurin competitively inhibits PKC beta I (IC50: 4.7 nM) in an ATP-dependent manner. Ruboxistaurin is able to act on PKC beta II (IC50: 5.9 nM).
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25 mg$691 1-2 weeks
50 mg$898 1-2 weeks
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Product Introduction

Bioactivity
Description
Ruboxistaurin (LY333531) is a selective, orally active PKC beta inhibitor with a Ki value of 2 nM. Ruboxistaurin competitively inhibits PKC beta I (IC50: 4.7 nM) in an ATP-dependent manner. Ruboxistaurin is able to act on PKC beta II (IC50: 5.9 nM).
Targets&IC50
PKCδ:250 nM, PKCη:52 nM, PKCε:600 nM, PKCα:360 nM, PKCβII:5.9 nM, PKCγ:300 nM, PKCβI:4.7 nM
Chemical Properties
Molecular Weight468.55
FormulaC28H28N4O3
Cas No.169939-94-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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