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AWZ1066S

Name: AWZ1066S
Brand: TargetMol
SKU: T10423
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T10423Cas No. 2239272-16-1

AWZ1066S is a highly specific anti-Wolbachia drug candidate for the short-course treatment of filariasis (EC50: 2.5 nM in cell assay).

AWZ1066S

🥰Excellent

Purity: 98.32%

Catalog No. T10423Cas No. 2239272-16-1

AWZ1066S is a highly specific anti-Wolbachia drug candidate for the short-course treatment of filariasis (EC50: 2.5 nM in cell assay).

Pack Size	Price	Availability
1 mg	$37	In Stock
5 mg	$85	In Stock
10 mg	$155	In Stock
25 mg	$248	In Stock
50 mg	$363	In Stock
100 mg	$538	In Stock
200 mg	$767	In Stock
1 mL x 10 mM (in DMSO)	$94	In Stock

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Batch Information

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Purity:98.32%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

AWZ1066S is a highly specific anti-Wolbachia drug candidate for the short-course treatment of filariasis (EC50: 2.5 nM in cell assay).

Chemical Properties

Molecular Weight	404.39
Formula	C₁₉H₁₉F₃N₆O
Cas No.	2239272-16-1
Smiles	C[C@H]1COCCN1c1nc(NCc2cccnc2C(F)(F)F)c2cccnc2n1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 120 mg/mL (296.74 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4729 mL	12.3643 mL	24.7286 mL	123.6430 mL
5 mM	0.4946 mL	2.4729 mL	4.9457 mL	24.7286 mL
10 mM	0.2473 mL	1.2364 mL	2.4729 mL	12.3643 mL
20 mM	0.1236 mL	0.6182 mL	1.2364 mL	6.1822 mL
50 mM	0.0495 mL	0.2473 mL	0.4946 mL	2.4729 mL
100 mM	0.0247 mL	0.1236 mL	0.2473 mL	1.2364 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc