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Chlorothiazide

Name: Chlorothiazide
Brand: TargetMol
SKU: T0677
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0677Cas No. 58-94-6

Alias Diuril, Chlotride, Chlorothiazid

Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.

Chlorothiazide

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Purity: 98.91%

Catalog No. T0677Alias Diuril, Chlotride, ChlorothiazidCas No. 58-94-6

Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
200 mg	$30	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:98.91%

Color:White

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COA

Product Introduction

Bioactivity

Description	Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.
Targets&IC50	Antihypertensive:3.8 mM
Synonyms	Diuril, Chlotride, Chlorothiazid

Chemical Properties

Molecular Weight	295.72
Formula	C₇H₆ClN₃O₄S₂
Cas No.	58-94-6
Smiles	NS(=O)(=O)c1c(Cl)cc2NC=NS(=O)(=O)c2c1
Relative Density.	1.7303 g/cm3 (Estimated)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (185.99 mM), Sonication is recommended.

Ethanol: <1 mg/mL

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (11.16 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3816 mL	16.9079 mL	33.8158 mL	169.0789 mL
5 mM	0.6763 mL	3.3816 mL	6.7632 mL	33.8158 mL
10 mM	0.3382 mL	1.6908 mL	3.3816 mL	16.9079 mL
20 mM	0.1691 mL	0.8454 mL	1.6908 mL	8.4539 mL
50 mM	0.0676 mL	0.3382 mL	0.6763 mL	3.3816 mL
100 mM	0.0338 mL	0.1691 mL	0.3382 mL	1.6908 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc