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Harmine hydrochloride

🥰Excellent
Catalog No. T2811Cas No. 343-27-1
Alias telepathine hydrochloride

Harmine hydrochloride (telepathine hydrochloride) is extracted from Peganum Harmala Genus.

Harmine hydrochloride
Other Forms of Harmine hydrochloride:
HarmineT1711442-51-3
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Harmine hydrochloride

🥰Excellent
Purity: 99.84%
Catalog No. T2811Alias telepathine hydrochlorideCas No. 343-27-1
Harmine hydrochloride (telepathine hydrochloride) is extracted from Peganum Harmala Genus.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$41In StockIn Stock
100 mg$66In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:99.84%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Harmine hydrochloride (telepathine hydrochloride) is extracted from Peganum Harmala Genus.
Targets&IC50
5-HT2A receptor:397 nM (Ki), DYRK2:1.9 μM, DYRK1A:33 nM, MNB:149 nM, DYRK1B:166 nM
Synonymstelepathine hydrochloride
Chemical Properties
Molecular Weight248.71
FormulaC13H13ClN2O
Cas No.343-27-1
SmilesCl.COc1ccc2c(c1)[nH]c1c(C)nccc21
Relative Density.no data available
ColorYellow
AppearanceSolid
Storage & Solubility Information
Storagekeep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 2 mg/mL (8.04 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0207 mL20.1037 mL40.2075 mL201.0374 mL
5 mM0.8041 mL4.0207 mL8.0415 mL40.2075 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

telepathine HydrochlorideTelepathineSerotonin ReceptorInhibitorinhibitHarmine hydrochlorideHarmine HydrochlorideHarmineGluR1DYRK2DYRK1BDYRK1ADYRKDual specificity tyrosine regulated kinaseDual specificity tyrosine phosphorylation regulated kinase5-hydroxytryptamine Receptor5HTReceptor5-HT Receptor5HT Receptor
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