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Dihydrosanguinarine
🥰Excellent
Catalog No. T4S2012Cas No. 3606-45-9
Alias Dihydro Sanguinarine, 13,14-Dihydrosanguinarine
Dihydrosanguinarine, a natural compound isolated from the leaves of [Macleaya microcarpa], exhibits antifungal and anticancer activity.
Dihydrosanguinarine
🥰Excellent
Purity: 98.93%
Catalog No. T4S2012Alias Dihydro Sanguinarine, 13,14-DihydrosanguinarineCas No. 3606-45-9
Dihydrosanguinarine, a natural compound isolated from the leaves of [Macleaya microcarpa], exhibits antifungal and anticancer activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $64 | In Stock | |
| 5 mg | $189 | In Stock | |
| 10 mg | $313 | In Stock | |
| 25 mg | $528 | In Stock | |
| 50 mg | $752 | In Stock | |
| 100 mg | $987 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $198 | In Stock |
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Purity:98.93%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Dihydrosanguinarine, a natural compound isolated from the leaves of [Macleaya microcarpa], exhibits antifungal and anticancer activity. |
| In vitro | Dihydro Sanguinarine may cause both necrosis and apoptosis of HL-60 cells[1]. |
| In vivo | Dihydrosanguinarine was?effective against I. multifiliis with median effective concentration (EC(50)) values of 5.18mg/l.?The acute toxicities (LC(50)) of dihydrosanguinarine and dihydrochelerythrine for richadsin was 13.3mg/l,?The overall results provided important information for the potential application of dihydrosanguinarine and dihydrochelerythrine in the therapy of serious infection caused by I. multifiliis[2]. |
| Synonyms | Dihydro Sanguinarine, 13,14-Dihydrosanguinarine |
| Molecular Weight | 333.34 |
| Formula | C20H15NO4 |
| Cas No. | 3606-45-9 |
| Smiles | CN1Cc2c3OCOc3ccc2-c2ccc3cc4OCOc4cc3c12 |
| Relative Density. | 1.426g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 5.2 mg/mL (15.6 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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