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Dihydrosanguinarine, a natural compound isolated from the leaves of [Macleaya microcarpa], exhibits antifungal and anticancer activity.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $64 | In Stock | In Stock | |
| 5 mg | $189 | In Stock | In Stock | |
| 10 mg | $313 | In Stock | In Stock | |
| 25 mg | $528 | In Stock | In Stock | |
| 50 mg | $752 | In Stock | In Stock | |
| 100 mg | $987 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $198 | In Stock | In Stock |
| Description | Dihydrosanguinarine, a natural compound isolated from the leaves of [Macleaya microcarpa], exhibits antifungal and anticancer activity. |
| In vitro | Dihydro Sanguinarine may cause both necrosis and apoptosis of HL-60 cells[1]. |
| In vivo | Dihydrosanguinarine was?effective against I. multifiliis with median effective concentration (EC(50)) values of 5.18mg/l.?The acute toxicities (LC(50)) of dihydrosanguinarine and dihydrochelerythrine for richadsin was 13.3mg/l,?The overall results provided important information for the potential application of dihydrosanguinarine and dihydrochelerythrine in the therapy of serious infection caused by I. multifiliis[2]. |
| Synonyms | Dihydro Sanguinarine, 13,14-Dihydrosanguinarine |
| Molecular Weight | 333.34 |
| Formula | C20H15NO4 |
| Cas No. | 3606-45-9 |
| Smiles | CN1Cc2c3OCOc3ccc2-c2ccc3cc4OCOc4cc3c12 |
| Relative Density. | 1.426g/cm3 |
| Storage | keep away from moisture,keep away from direct sunlight | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 5.2 mg/mL (15.6 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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