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Seratrodast

Name: Seratrodast
Brand: TargetMol
SKU: T0212
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T0212Cas No. 112665-43-7

Alias ABT-001, AA 2414

Seratrodast (ABT-001) (INN), a thromboxane A2 (TXA2) receptor (TP receptor) antagonist, is mainly used in the therapy of asthma. It was the first TP receptor antagonist developed as an anti-asthmatic drug and attained marketing qualification in Japan in 1997.

Seratrodast

🥰Excellent

Purity: 99.69%

Catalog No. T0212Alias ABT-001, AA 2414Cas No. 112665-43-7

Pack Size	Price	Availability
10 mg	$34	In Stock
25 mg	$61	In Stock
50 mg	$85	In Stock
100 mg	$123	In Stock
500 mg	$297	In Stock
1 mL x 10 mM (in DMSO)	$37	In Stock

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Batch Information

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Purity:99.69%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Seratrodast (ABT-001) (INN), a thromboxane A2 (TXA2) receptor (TP receptor) antagonist, is mainly used in the therapy of asthma. It was the first TP receptor antagonist developed as an anti-asthmatic drug and attained marketing qualification in Japan in 1997.
Synonyms	ABT-001, AA 2414

Chemical Properties

Molecular Weight	354.44
Formula	C₂₂H₂₆O₄
Cas No.	112665-43-7
Smiles	C(CCCCCC(O)=O)(C1=C(C)C(=O)C(C)=C(C)C1=O)C2=CC=CC=C2
Relative Density.	1.14 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (141.07 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8214 mL	14.1068 mL	28.2135 mL	141.0676 mL
5 mM	0.5643 mL	2.8214 mL	5.6427 mL	28.2135 mL
10 mM	0.2821 mL	1.4107 mL	2.8214 mL	14.1068 mL
20 mM	0.1411 mL	0.7053 mL	1.4107 mL	7.0534 mL
50 mM	0.0564 mL	0.2821 mL	0.5643 mL	2.8214 mL
100 mM	0.0282 mL	0.1411 mL	0.2821 mL	1.4107 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc