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Seratrodast

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Catalog No. T0212Cas No. 112665-43-7
Alias ABT-001, AA 2414

Seratrodast (ABT-001) (INN), a thromboxane A2 (TXA2) receptor (TP receptor) antagonist, is mainly used in the therapy of asthma. It was the first TP receptor antagonist developed as an anti-asthmatic drug and attained marketing qualification in Japan in 1997.

Seratrodast

Seratrodast

😃Good
Purity: 99.69%
Catalog No. T0212Alias ABT-001, AA 2414Cas No. 112665-43-7
Seratrodast (ABT-001) (INN), a thromboxane A2 (TXA2) receptor (TP receptor) antagonist, is mainly used in the therapy of asthma. It was the first TP receptor antagonist developed as an anti-asthmatic drug and attained marketing qualification in Japan in 1997.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$34In StockIn Stock
25 mg$61In StockIn Stock
50 mg$85In StockIn Stock
100 mg$123In StockIn Stock
500 mg$297-In Stock
1 mL x 10 mM (in DMSO)$37In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.69%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
Seratrodast (ABT-001) (INN), a thromboxane A2 (TXA2) receptor (TP receptor) antagonist, is mainly used in the therapy of asthma. It was the first TP receptor antagonist developed as an anti-asthmatic drug and attained marketing qualification in Japan in 1997.
SynonymsABT-001, AA 2414
Chemical Properties
Molecular Weight354.44
FormulaC22H26O4
Cas No.112665-43-7
SmilesC(CCCCCC(O)=O)(C1=C(C)C(=O)C(C)=C(C)C1=O)C2=CC=CC=C2
Relative Density.1.14 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (141.07 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+90% Saline: 2.5 mg/mL (7.05 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8214 mL14.1068 mL28.2135 mL141.0676 mL
5 mM0.5643 mL2.8214 mL5.6427 mL28.2135 mL
10 mM0.2821 mL1.4107 mL2.8214 mL14.1068 mL
20 mM0.1411 mL0.7053 mL1.4107 mL7.0534 mL
50 mM0.0564 mL0.2821 mL0.5643 mL2.8214 mL
100 mM0.0282 mL0.1411 mL0.2821 mL1.4107 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TXA2RSeratrodastProstaglandinReceptorProstaglandin ReceptorInhibitorinhibitCOXABT001ABT 001AA-2414AA2414
Related Tags: buy Seratrodast | purchase Seratrodast | Seratrodast cost | order Seratrodast | Seratrodast chemical structure | Seratrodast formula | Seratrodast molecular weight
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