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MALT1-IN-14 (comp 2) is a potent and selective MALT1 inhibitor with an IC50 value of 0.081 μM, widely utilized in immunology and oncology research to suppress MALT1 protease activity, dissect NF-κB signaling cascades, and evaluate therapeutic approaches targeting lymphoid malignancies and inflammatory diseases driven by dysregulated immune activation.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | Inquiry | 3-6 months | 3-6 months | |
| 50 mg | Inquiry | 3-6 months | 3-6 months | |
| 100 mg | Inquiry | 3-6 months | 3-6 months |
| Description | MALT1-IN-14 (comp 2) is a potent and selective MALT1 inhibitor with an IC50 value of 0.081 μM, widely utilized in immunology and oncology research to suppress MALT1 protease activity, dissect NF-κB signaling cascades, and evaluate therapeutic approaches targeting lymphoid malignancies and inflammatory diseases driven by dysregulated immune activation. |
| Targets&IC50 | MALT1:0.081 μM |
| In vitro | In biochemical protease assays, MALT1-IN-14 inhibited MALT1 enzymatic activity with an IC50 of 0.081 μM [1]. |
| Molecular Weight | 618.02 |
| Formula | C26H25ClF5N5O3S |
| Cas No. | 3047242-55-4 |
| Smiles | C(F)(F)(F)[C@@]1(C)C2=C(N(C1)C3=CC=C(C=C3)[C@H]4[C@@](C(N[C@@H]5C[C@@H](S(C)(=O)=O)C5)=O)(C)C4(F)F)C=NC=6N2N=C(Cl)C6 |
| Storage | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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