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BS194

Name: BS194
Brand: TargetMol
SKU: T7698
Price: 73 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T7698Cas No. 1092443-55-4

BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.

BS194

🥰Excellent

Purity: 99.85%

Catalog No. T7698Cas No. 1092443-55-4

BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.

Pack Size	Price	Availability
1 mg	$73	In Stock
5 mg	$179	In Stock
10 mg	$278	In Stock
25 mg	$473	In Stock
50 mg	$678	In Stock
100 mg	$948	In Stock
1 mL x 10 mM (in DMSO)	$253	In Stock

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Batch Information

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Purity:99.85%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.
Targets&IC50	CDK1:30 nM, CDK7:250 nM, CDK9:90 nM, CDK2:3 nM, CDK5:30 nM

Chemical Properties

Molecular Weight	385.46
Formula	C₂₀H₂₇N₅O₃
Cas No.	1092443-55-4
Smiles	C(C)(C)C1=C2N(C(NCC3=CC=CC=C3)=CC(N[C@H]([C@@H](CO)O)CO)=N2)N=C1
Relative Density.	1.33 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (71.34 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5943 mL	12.9715 mL	25.9430 mL	129.7151 mL
5 mM	0.5189 mL	2.5943 mL	5.1886 mL	25.9430 mL
10 mM	0.2594 mL	1.2972 mL	2.5943 mL	12.9715 mL
20 mM	0.1297 mL	0.6486 mL	1.2972 mL	6.4858 mL
50 mM	0.0519 mL	0.2594 mL	0.5189 mL	2.5943 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc