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Tyrosine kinase-IN-7

🥰Excellent
Catalog No. T77746Cas No. 345615-74-9

Tyrosine kinase-IN-7 is a potent inhibitor of the tyrosine kinase EGFR, inhibiting EGFR(WT) and EGFR(T790M) and showing anti-cancer and anti-tumor activity in a variety of cancer cell lines. Tyrosine kinase-IN-7 has potential anti-inflammatory and antiviral activities.

Tyrosine kinase-IN-7

Tyrosine kinase-IN-7

🥰Excellent
Purity: 99.93%
Catalog No. T77746Cas No. 345615-74-9
Tyrosine kinase-IN-7 is a potent inhibitor of the tyrosine kinase EGFR, inhibiting EGFR(WT) and EGFR(T790M) and showing anti-cancer and anti-tumor activity in a variety of cancer cell lines. Tyrosine kinase-IN-7 has potential anti-inflammatory and antiviral activities.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$30In StockIn Stock
10 mg$40In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.93%
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Product Introduction

Bioactivity
Description
Tyrosine kinase-IN-7 is a potent inhibitor of the tyrosine kinase EGFR, inhibiting EGFR(WT) and EGFR(T790M) and showing anti-cancer and anti-tumor activity in a variety of cancer cell lines. Tyrosine kinase-IN-7 has potential anti-inflammatory and antiviral activities.
Targets&IC50
EGFR (T790M):0.956 μM, EGFR (WT):0.63 μM
Chemical Properties
Molecular Weight297.38
FormulaC16H15N3OS
Cas No.345615-74-9
SmilesOC1=CC=C(NC2=NC=NC3=C2C2=C(CCCC2)S3)C=C1
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 5.5 mg/mL (18.49 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3627 mL16.8135 mL33.6270 mL168.1350 mL
5 mM0.6725 mL3.3627 mL6.7254 mL33.6270 mL
10 mM0.3363 mL1.6814 mL3.3627 mL16.8135 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

TyrosinekinaseIN7EGFRAntiviral
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