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JNK-IN-13

Name: JNK-IN-13
Brand: TargetMol
SKU: T77694
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77694Cas No. 345986-38-1

JNK-IN-13 is a selective and potent JNK inhibitor that inhibits JNK3 and JNK2 and can be used in the study of diabetes, inflammation, and neurological disorders.

JNK-IN-13

🥰Excellent

Purity: 98.74%

Catalog No. T77694Cas No. 345986-38-1

JNK-IN-13 is a selective and potent JNK inhibitor that inhibits JNK3 and JNK2 and can be used in the study of diabetes, inflammation, and neurological disorders.

Pack Size	Price	Availability
10 mg	$33	In Stock
25 mg	$52	In Stock
50 mg	$85	In Stock

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Batch Information

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Purity:98.74%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	JNK-IN-13 is a selective and potent JNK inhibitor that inhibits JNK3 and JNK2 and can be used in the study of diabetes, inflammation, and neurological disorders.
Targets&IC50	JNK2:500 nM, JNK3:290 nM

Chemical Properties

Molecular Weight	286.74
Formula	C₁₃H₇ClN₄S
Cas No.	345986-38-1
Smiles	Clc1nccc(n1)C(C#N)c1nc2ccccc2s1

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 20 mg/mL (69.75 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4875 mL	17.4374 mL	34.8748 mL	174.3740 mL
5 mM	0.6975 mL	3.4875 mL	6.9750 mL	34.8748 mL
10 mM	0.3487 mL	1.7437 mL	3.4875 mL	17.4374 mL
20 mM	0.1744 mL	0.8719 mL	1.7437 mL	8.7187 mL
50 mM	0.0697 mL	0.3487 mL	0.6975 mL	3.4875 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc