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Thonzylamine

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Catalog No. T4563Cas No. 91-85-0
Alias neohetramine

Thonzylamine (neohetramine) is an antihistamine and anticholinergic drug. It is available as combination products with Clofedanol or Phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.

Thonzylamine
Other Forms of Thonzylamine:
Thonzylamine hydrochlorideT2101463-56-9
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Thonzylamine

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Purity: 99.45%
Catalog No. T4563Alias neohetramineCas No. 91-85-0
Thonzylamine (neohetramine) is an antihistamine and anticholinergic drug. It is available as combination products with Clofedanol or Phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$30In StockIn Stock
5 mg$44In StockIn Stock
10 mg$68In StockIn Stock
25 mg$129In StockIn Stock
50 mg$197In StockIn Stock
100 mg$289BackorderBackorder
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.45%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Thonzylamine (neohetramine) is an antihistamine and anticholinergic drug. It is available as combination products with Clofedanol or Phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.
Synonymsneohetramine
Chemical Properties
Molecular Weight286.37
FormulaC16H22N4O
Cas No.91-85-0
SmilesN(CC1=CC=C(OC)C=C1)(CCN(C)C)C=2N=CC=CN2
Relative Density.1.121g/cm3
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 199 mM, Sonication is recommended.
H2O: 199 mM, Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.98 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM3.4920 mL17.4599 mL34.9199 mL174.5993 mL
5 mM0.6984 mL3.4920 mL6.9840 mL34.9199 mL
10 mM0.3492 mL1.7460 mL3.4920 mL17.4599 mL
20 mM0.1746 mL0.8730 mL1.7460 mL8.7300 mL
50 mM0.0698 mL0.3492 mL0.6984 mL3.4920 mL
100 mM0.0349 mL0.1746 mL0.3492 mL1.7460 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ThonzylaminenasalInhibitorinhibithypersensitivityHistamineReceptorHistamine ReceptorhistamineH1 receptorconjunctivitiscongestionantihistaminicantianaphylacticallergic
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