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Benzyl selenocyanate

Name: Benzyl selenocyanate
Brand: TargetMol
SKU: T40560
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T40560Cas No. 4671-93-6

Benzyl selenocyanate is a chemopreventive agent that effectively inhibits chemically induced tumors at both initiation and postinitiation stages in animal models. It acts as a potent inhibitor of DNA (cytosine-5)-methyltransferase (Mtase) with an IC50 of 8.4 μM.

Benzyl selenocyanate

🥰Excellent

Purity: 99.2%

Catalog No. T40560Cas No. 4671-93-6

Pack Size	Price	Availability
1 mg	$40	In Stock
5 mg	$98	In Stock
10 mg	$147	In Stock
25 mg	$248	In Stock
50 mg	$368	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.2%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Benzyl selenocyanate is a chemopreventive agent that effectively inhibits chemically induced tumors at both initiation and postinitiation stages in animal models. It acts as a potent inhibitor of DNA (cytosine-5)-methyltransferase (Mtase) with an IC50 of 8.4 μM.
Targets&IC50	Mtase:8.4 µM
In vitro	Selenite, Benzyl selenocyanate and p-XSC inhibited Mtase extracted from human colon cancer with IC50 values of 3.8, 8.1 and 5.2 μM, respectively[1].

Chemical Properties

Molecular Weight	196.11
Formula	C₈H₇NSe
Cas No.	4671-93-6
Smiles	N#C[Se]CC=1C=CC=CC1
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (407.93 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (16.83 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.0992 mL	25.4959 mL	50.9918 mL	254.9590 mL
5 mM	1.0198 mL	5.0992 mL	10.1984 mL	50.9918 mL
10 mM	0.5099 mL	2.5496 mL	5.0992 mL	25.4959 mL
20 mM	0.2550 mL	1.2748 mL	2.5496 mL	12.7479 mL
50 mM	0.1020 mL	0.5099 mL	1.0198 mL	5.0992 mL
100 mM	0.0510 mL	0.2550 mL	0.5099 mL	2.5496 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc