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MK-8245 analog

🥰Excellent
Catalog No. T20950Cas No. 1030612-87-3
Alias MK-8245-analog, MK 8245 analog

MK-8245 analog is an analog of MK-8245 which is a liver-targeted Inhibitor of Stearoyl-CoA Desaturase (SCD). It is useful for the Treatment of Dyslipidemia and Diabetes.

MK-8245 analog

MK-8245 analog

🥰Excellent
Purity: 99.85%
Catalog No. T20950Alias MK-8245-analog, MK 8245 analogCas No. 1030612-87-3
MK-8245 analog is an analog of MK-8245 which is a liver-targeted Inhibitor of Stearoyl-CoA Desaturase (SCD). It is useful for the Treatment of Dyslipidemia and Diabetes.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$89In StockIn Stock
2 mg$126In StockIn Stock
5 mg$197In StockIn Stock
10 mg$298In StockIn Stock
25 mg$476In StockIn Stock
50 mg$678In StockIn Stock
100 mg$912In StockIn Stock
200 mg$1,190In StockIn Stock
1 mL x 10 mM (in DMSO)$238In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.85%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
MK-8245 analog is an analog of MK-8245 which is a liver-targeted Inhibitor of Stearoyl-CoA Desaturase (SCD). It is useful for the Treatment of Dyslipidemia and Diabetes.
SynonymsMK-8245-analog, MK 8245 analog
Chemical Properties
Molecular Weight484.3
FormulaC16H15BrFN7O3S
Cas No.1030612-87-3
SmilesC(C(O)=O)N1N=C(C=2SC(=NN2)N3CCC(OC4=C(Br)C=CC(F)=C4)CC3)N=N1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (113.57 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0648 mL10.3242 mL20.6484 mL103.2418 mL
5 mM0.4130 mL2.0648 mL4.1297 mL20.6484 mL
10 mM0.2065 mL1.0324 mL2.0648 mL10.3242 mL
20 mM0.1032 mL0.5162 mL1.0324 mL5.1621 mL
50 mM0.0413 mL0.2065 mL0.4130 mL2.0648 mL
100 mM0.0206 mL0.1032 mL0.2065 mL1.0324 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MK-8245 analogMK8245 analog
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