Powder: -20°C for 3 years | In solvent: -80°C for 1 year
G12Si-5 is a covalent inhibitor of the K-RasG12S mutant with a Ki value of 26 μM. G12Si-5 binds to the S-IIP structural domain and inhibits oncogenic signalling. g12Si-5 reduces ERK phosphorylation levels in KRAS G12S mutant cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 1,520.00 | |
50 mg | 10-14 weeks | $ 1,980.00 | |
100 mg | 10-14 weeks | $ 2,500.00 |
Description | G12Si-5 is a covalent inhibitor of the K-RasG12S mutant with a Ki value of 26 μM. G12Si-5 binds to the S-IIP structural domain and inhibits oncogenic signalling. g12Si-5 reduces ERK phosphorylation levels in KRAS G12S mutant cells. |
Molecular Weight | 574.05 |
Formula | C31H29ClFN5O3 |
CAS No. | 2946593-46-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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G12Si-5 2946593-46-8 inhibitor inhibit