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N-Desethyl amodiaquine dihydrochloride

🥰Excellent
Catalog No. T12154LCas No. 79049-30-2

N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent and the major biologically active amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively.

N-Desethyl amodiaquine dihydrochloride
Other Forms of N-Desethyl amodiaquine dihydrochloride:

N-Desethyl amodiaquine dihydrochloride

🥰Excellent
Purity: 98.83%
Catalog No. T12154LCas No. 79049-30-2
N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent and the major biologically active amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$68In StockIn Stock
5 mg$137In StockIn Stock
10 mg$229In StockIn Stock
25 mg$482In StockIn Stock
50 mg$783In StockIn Stock
100 mg$1,280In StockIn Stock
1 mL x 10 mM (in DMSO)$119In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:98.83%
Appearance:Solid
Color:Yellow
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent and the major biologically active amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively.
Chemical Properties
Molecular Weight400.73
FormulaC18H20Cl3N3O
Cas No.79049-30-2
SmilesCl.Cl.CCNCc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (149.73 mM), Sonication is recommended.
H2O: 100 mg/mL (249.54 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.99 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.4954 mL12.4772 mL24.9545 mL124.7723 mL
5 mM0.4991 mL2.4954 mL4.9909 mL24.9545 mL
10 mM0.2495 mL1.2477 mL2.4954 mL12.4772 mL
20 mM0.1248 mL0.6239 mL1.2477 mL6.2386 mL
50 mM0.0499 mL0.2495 mL0.4991 mL2.4954 mL
100 mM0.0250 mL0.1248 mL0.2495 mL1.2477 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ParasiteN-Desethyl amodiaquine DihydrochlorideNDesethyl amodiaquine dihydrochlorideN-Desethyl amodiaquineN Desethyl amodiaquine dihydrochlorideInhibitorinhibit
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