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N-Desethyl amodiaquine dihydrochloride

🥰Excellent
Catalog No. T12154LCas No. 79049-30-2

N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent and the major biologically active amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively.

N-Desethyl amodiaquine dihydrochloride
Other Forms of N-Desethyl amodiaquine dihydrochloride:

N-Desethyl amodiaquine dihydrochloride

🥰Excellent
Purity: 98.83%
Catalog No. T12154LCas No. 79049-30-2
N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent and the major biologically active amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$68In StockIn Stock
5 mg$137In StockIn Stock
10 mg$229In StockIn Stock
25 mg$482In StockIn Stock
50 mg$783In StockIn Stock
100 mg$1,280In StockIn Stock
1 mL x 10 mM (in DMSO)$119In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.83%
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Product Introduction

Bioactivity
Description
N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent and the major biologically active amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively.
Chemical Properties
Molecular Weight400.73
FormulaC18H20Cl3N3O
Cas No.79049-30-2
SmilesCl.Cl.CCNCc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (149.73 mM), Sonication is recommended.
H2O: 100 mg/mL (249.54 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.99 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.4954 mL12.4772 mL24.9545 mL124.7723 mL
5 mM0.4991 mL2.4954 mL4.9909 mL24.9545 mL
10 mM0.2495 mL1.2477 mL2.4954 mL12.4772 mL
20 mM0.1248 mL0.6239 mL1.2477 mL6.2386 mL
50 mM0.0499 mL0.2495 mL0.4991 mL2.4954 mL
100 mM0.0250 mL0.1248 mL0.2495 mL1.2477 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ParasiteN-Desethyl amodiaquine DihydrochlorideNDesethyl amodiaquine dihydrochlorideN-Desethyl amodiaquineN Desethyl amodiaquine dihydrochlorideInhibitorinhibit
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