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Nilofabicin

Name: Nilofabicin
Brand: TargetMol
SKU: T19642
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T19642Cas No. 934628-27-0

Alias CG-400549, CG400549, CG-0549, CG0549, CG 400549, CG 0549

Nilofabicin (CG-400549) is a potent inhibitor of enoyl-(acyl-carrier-protein) reductase fall(FabI) and can be used in studies about the treatment of complicated acute.

Nilofabicin

🥰Excellent

Purity: 98.66%

Catalog No. T19642Alias CG-400549, CG400549, CG-0549, CG0549, CG 400549, CG 0549Cas No. 934628-27-0

Nilofabicin (CG-400549) is a potent inhibitor of enoyl-(acyl-carrier-protein) reductase fall(FabI) and can be used in studies about the treatment of complicated acute.

Pack Size	Price	Availability
5 mg	$33	In Stock
10 mg	$48	In Stock
25 mg	$78	In Stock
50 mg	$125	In Stock
1 mL x 10 mM (in DMSO)	$38	In Stock

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Purity:98.66%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Nilofabicin (CG-400549) is a potent inhibitor of enoyl-(acyl-carrier-protein) reductase fall(FabI) and can be used in studies about the treatment of complicated acute.
Targets&IC50	S. aureus:0.5 μg/ml(MIC90)
In vitro	Nilofabicin had an MIC90 of 0.5 μg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin. Among 203 strains of Staphylococcus aureus, the MICs of Nilofabicin were 0.06 to 1.0 μg/ml, with MIC(50) and MIC(90) values of 0.25 μg/ml each. All strains were susceptible to linezolid and quinupristin-dalfopristin (MICs, 0.25 to 2.0 μg/ml)[3].
Synonyms	CG-400549, CG400549, CG-0549, CG0549, CG 400549, CG 0549

Chemical Properties

Molecular Weight	340.44
Formula	C₁₉H₂₀N₂O₂S
Cas No.	934628-27-0
Smiles	Cc1c(N)cccc1Cn1ccc(OCCc2cccs2)cc1=O
Relative Density.	1.273 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 95 mg/mL (279.05 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9374 mL	14.6869 mL	29.3738 mL	146.8688 mL
5 mM	0.5875 mL	2.9374 mL	5.8748 mL	29.3738 mL
10 mM	0.2937 mL	1.4687 mL	2.9374 mL	14.6869 mL
20 mM	0.1469 mL	0.7343 mL	1.4687 mL	7.3434 mL
50 mM	0.0587 mL	0.2937 mL	0.5875 mL	2.9374 mL
100 mM	0.0294 mL	0.1469 mL	0.2937 mL	1.4687 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc