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Dehydrocholic acid

Name: Dehydrocholic acid
Brand: TargetMol
SKU: T0408
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0408Cas No. 81-23-2

Alias Sanocholen, Felacrinos, Dehystolin, Decholin

Dehydrocholic acid (Dehystolin) is a synthetic bile acid, produced by the oxidation of cholic acid.

Dehydrocholic acid

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Purity: 98.58%

Catalog No. T0408Alias Sanocholen, Felacrinos, Dehystolin, DecholinCas No. 81-23-2

Dehydrocholic acid (Dehystolin) is a synthetic bile acid, produced by the oxidation of cholic acid.

Pack Size	Price	USA Warehouse	Global Warehouse
2 g	$34	-	In Stock
5 g	$53	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.58%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Dehydrocholic acid (Dehystolin) is a synthetic bile acid, produced by the oxidation of cholic acid.
In vivo	DHCA (dehydrocholic acid) infusion induces choleresis associated with reduced secretion of endogenous and/or exogenous biliary components[1].
Synonyms	Sanocholen, Felacrinos, Dehystolin, Decholin

Chemical Properties

Molecular Weight	402.52
Formula	C₂₄H₃₄O₅
Cas No.	81-23-2
Smiles	CC(CCC(O)=O)C1CCC2C3C(CC(=O)C12C)C1(C)CCC(=O)CC1CC3=O
Relative Density.	1.0687 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)

Ethanol: 12 mg/mL (29.81 mM), Sonication is recommended.

DMSO: 45 mg/mL (111.8 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Saline: 2 mg/mL (4.97 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4843 mL	12.4217 mL	24.8435 mL	124.2174 mL
5 mM	0.4969 mL	2.4843 mL	4.9687 mL	24.8435 mL
10 mM	0.2484 mL	1.2422 mL	2.4843 mL	12.4217 mL
20 mM	0.1242 mL	0.6211 mL	1.2422 mL	6.2109 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0497 mL	0.2484 mL	0.4969 mL	2.4843 mL
100 mM	0.0248 mL	0.1242 mL	0.2484 mL	1.2422 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc