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Et-29

Name: Et-29
Brand: TargetMol
SKU: T35347
Price: 63 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T35347Cas No. 2166487-23-4

Alias NRD167

Et-29 is a selective inhibitor of SIRT5 inhibitor with a Ki of 40 nM.

Et-29

🥰Excellent

Purity: 99.52%

Catalog No. T35347Alias NRD167Cas No. 2166487-23-4

Et-29 is a selective inhibitor of SIRT5 inhibitor with a Ki of 40 nM.

Pack Size	Price	Availability
1 mg	$63	In Stock
5 mg	$152	In Stock
10 mg	$247	In Stock
25 mg	$418	In Stock
50 mg	$595	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.52%

Resource Download

COA LCMS HPLC HNMR

Product Introduction

Bioactivity

Description	Et-29 is a selective inhibitor of SIRT5 inhibitor with a Ki of 40 nM.
Targets&IC50	SIRT5:40 nM (Ki)
Alias	NRD167

Chemical Properties

Molecular Weight	666.83
Formula	C₃₄H₄₆N₆O₆S
Cas No.	2166487-23-4
Smiles	CCOC(=O)CCNC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC(C)C

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200 mg/mL (299.93 mM)

In Vivo Formulation

5% DMSO+40% PEG300+5% Tween-80+50% ddH2O: 10 mg/mL (15 mM)

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.4996 mL	7.4982 mL	14.9963 mL	74.9816 mL
5 mM	0.2999 mL	1.4996 mL	2.9993 mL	14.9963 mL
10 mM	0.1500 mL	0.7498 mL	1.4996 mL	7.4982 mL
20 mM	0.0750 mL	0.3749 mL	0.7498 mL	3.7491 mL
50 mM	0.0300 mL	0.1500 mL	0.2999 mL	1.4996 mL
100 mM	0.0150 mL	0.0750 mL	0.1500 mL	0.7498 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc