Shopping Cart
Remove All
Your shopping cart is currently empty
MAT2A inhibitor 6
😃Good
Catalog No. T89595Cas No. 2447686-21-5
MAT2A inhibitor 6 (Compound 3N-h) is a compound renowned for its specificity, oral activity, and yellow fluorescence as a MAT2A inhibitor (IC50=26 nM). It enables visualization of MAT2A both in vitro and in vivo (λex=430 nm, λem= 585 nm). Additionally, MAT2A inhibitor 6 induces apoptosis and possesses anticancer properties, making it useful for cancer research.
MAT2A inhibitor 6
😃Good
Catalog No. T89595Cas No. 2447686-21-5
MAT2A inhibitor 6 (Compound 3N-h) is a compound renowned for its specificity, oral activity, and yellow fluorescence as a MAT2A inhibitor (IC50=26 nM). It enables visualization of MAT2A both in vitro and in vivo (λex=430 nm, λem= 585 nm). Additionally, MAT2A inhibitor 6 induces apoptosis and possesses anticancer properties, making it useful for cancer research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | MAT2A inhibitor 6 (Compound 3N-h) is a compound renowned for its specificity, oral activity, and yellow fluorescence as a MAT2A inhibitor (IC50=26 nM). It enables visualization of MAT2A both in vitro and in vivo (λex=430 nm, λem= 585 nm). Additionally, MAT2A inhibitor 6 induces apoptosis and possesses anticancer properties, making it useful for cancer research. |
| In vitro | MAT2A inhibitor 6 (Compound 3N-h) significantly suppresses the proliferation of HCT-116 (MTAP KO) cells with an IC50 value of 0.1 μM over 72 hours. At a concentration of 1 μM and a duration of 24 hours, it also induces cell apoptosis (43% of cells in early or late-stage apoptosis) but is virtually non-toxic to wild-type HCT-116 cells. |
| In vivo | MAT2A inhibitor 6 (Compound 3N-h) (50 mg/kg; ) demonstrated antitumor activity by inhibiting the growth of HCT-116 (MTAP KO) tumors in Balb/c mice carrying the HCT-116 (MTAP KO) tumor. |
| Molecular Weight | 463.44 |
| Formula | C24H19F2N5O3 |
| Cas No. | 2447686-21-5 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy MAT2A inhibitor 6 | purchase MAT2A inhibitor 6 | MAT2A inhibitor 6 cost | order MAT2A inhibitor 6 | MAT2A inhibitor 6 chemical structure | MAT2A inhibitor 6 in vivo | MAT2A inhibitor 6 in vitro | MAT2A inhibitor 6 formula | MAT2A inhibitor 6 molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.