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Rasarfin
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Catalog No. T9407Cas No. 674359-73-0
Rasarfin inhibits Ras and ARF6.
Rasarfin
Copy Product Info🥰Excellent
Purity: 97.98%
Catalog No. T9407Cas No. 674359-73-0
Rasarfin inhibits Ras and ARF6.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $34 | In Stock | In Stock | |
| 5 mg | $73 | In Stock | In Stock | |
| 10 mg | $118 | In Stock | In Stock | |
| 25 mg | $215 | In Stock | In Stock | |
| 50 mg | $358 | In Stock | In Stock | |
| 100 mg | $511 | In Stock | In Stock | |
| 200 mg | $689 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $80 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
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Purity:97.98%
Appearance:solid
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Rasarfin inhibits Ras and ARF6. |
| In vitro | Rasarfin resulted in a dose-dependent reduction in cell growth in MDA-MB-231 cells.After 48 and 72?h of treatment, Rasarfin modestly decreased in a dose-dependent manner the metabolic activity of cancer cells compared to cells treated with DMSO.However, compared to Doxorubicin which potently killed cells, cell viability was not affected by Rasarfin treatment. Rasarfin inhibited proliferation of A549 lung cancer cells, which have increased Ras and EGFR activity52. Similar to the anti-proliferative effect on MDA-MB-231 cells, A549 cell growth inhibition at 5 and 10?μM of Rasarfin,more important cell viability effects of Rasarfin on A549 cells than MDA-MB-231 cells at 10?μM of Rasarfin treatment[1]. |
| Molecular Weight | 425.91 |
| Formula | C23H24ClN3O3 |
| Cas No. | 674359-73-0 |
| Smiles | CC(C)C(=O)N1CCN(CC1)c1ccc(NC(=O)c2cc3ccccc3o2)cc1Cl |
| Relative Density. | 1.309 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (140.87 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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