Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HDAC-IN-40 is a potent alkoxyamide-based HDAC inhibitor with Ki of 60 nM and 30 nM for HDAC2 and HDAC6, respectively. HDAC-IN-40 had antitumor effects
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 51.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 197.00 | |
25 mg | In stock | $ 455.00 | |
50 mg | In stock | $ 672.00 | |
100 mg | In stock | $ 956.00 |
Description | HDAC-IN-40 is a potent alkoxyamide-based HDAC inhibitor with Ki of 60 nM and 30 nM for HDAC2 and HDAC6, respectively. HDAC-IN-40 had antitumor effects |
In vitro | HDAC-IN-40 shows antiproliferative activity against the cell line A2780 and Cal27 with IC50 values of 0.89 µM and 0.72 µM, respectively. HDAC-IN-40 induces accumulation of acetyl α-tubulin in Cal27 and Cal27CisR. HDAC-IN-40 enhances the Cisplatin-induced cytotoxicity via caspase-3/7 activation[1]. |
Molecular Weight | 326.35 |
Formula | C15H22N2O6 |
CAS No. | 2463198-51-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 200 mg/mL (612.9 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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HDAC-IN-40 2463198-51-6 Chromatin/Epigenetic DNA Damage/DNA Repair HDAC HDACIN40 HDAC IN 40 inhibitor inhibit