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4'-Methylchrysoeriol

🥰Excellent
Catalog No. T10163Cas No. 4712-12-3
Alias 3',4'-dimethoxyluteolin

4'-Methylchrysoeriol is a potent inhibitor of cytochrome P450 enzymes (IC50: 19 nM for human P450 1B1-dependent EROD).

4'-Methylchrysoeriol

4'-Methylchrysoeriol

🥰Excellent
Purity: 98.4%
Catalog No. T10163Alias 3',4'-dimethoxyluteolinCas No. 4712-12-3
4'-Methylchrysoeriol is a potent inhibitor of cytochrome P450 enzymes (IC50: 19 nM for human P450 1B1-dependent EROD).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$117-In Stock
5 mg$289-In Stock
10 mg$463-In Stock
25 mg$823-In Stock
50 mg$1,290-In Stock
100 mg$2,080-In Stock
1 mL x 10 mM (in DMSO)$39-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.4%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
4'-Methylchrysoeriol is a potent inhibitor of cytochrome P450 enzymes (IC50: 19 nM for human P450 1B1-dependent EROD).
Targets&IC50
P450 1B1-dependent EROD (human):19 nM
In vitro
4'-Methylchrysoerio (3',4'-dimethoxyluteolin) inhibits human P450 1B1-dependent ethoxyallyl alcohol-O-deethylase (EROD) with an IC50 value of 19 nM. [1]
Synonyms3',4'-dimethoxyluteolin
Chemical Properties
Molecular Weight314.29
FormulaC17H14O6
Cas No.4712-12-3
SmilesO=C1C=C(OC=2C=C(O)C=C(O)C12)C=3C=CC(OC)=C(OC)C3
Relative Density.1.402g/cm3
ColorYellow
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: < 0.1 mg/mL (insoluble)
DMSO: 20 mg/mL (63.64 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1818 mL15.9089 mL31.8177 mL159.0887 mL
5 mM0.6364 mL3.1818 mL6.3635 mL31.8177 mL
10 mM0.3182 mL1.5909 mL3.1818 mL15.9089 mL
20 mM0.1591 mL0.7954 mL1.5909 mL7.9544 mL
50 mM0.0636 mL0.3182 mL0.6364 mL3.1818 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

P4504'-Methylchrysoeriol4'Methylchrysoeriol4' Methylchrysoeriol
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