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Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the slowly activating (IKs) and rapidly activating (IKr) components of the delayed rectifier potassium current

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $30 | In Stock | |
| 5 mg | $43 | In Stock | |
| 10 mg | $61 | In Stock | |
| 25 mg | $127 | In Stock | |
| 50 mg | $187 | In Stock |
| Description | Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the slowly activating (IKs) and rapidly activating (IKr) components of the delayed rectifier potassium current |
| In vivo | Azimilide has shown excellent efficacy (>85%) in suppressing supraventricular arrhythmias in a variety of dog models.?It also suppressed complex ventricular arrhythmias in infarcted dogs and, in a sudden death cardiac model, decreased mortality[1]. |
| Synonyms | NE-10064 Dihydrochloride |
| Molecular Weight | 530.88 |
| Formula | C23H30Cl3N5O3 |
| Cas No. | 149888-94-8 |
| Smiles | Cl.Cl.CN1CCN(CCCCN2C(=O)CN(\N=C\c3ccc(o3)-c3ccc(Cl)cc3)C2=O)CC1 |
| Relative Density. | 1.32g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
| Solubility Information | DMSO: 1.33 mg/mL (2.51 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
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