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V-11-0711 HCl

Catalog No. T29083L
Alias V-11-0711 HCl(1428339-47-2 Free base)

V-11-0711 HCl is a selective and highly effective choline kinase α (ChoKα) inhibitor that inhibits the catalytic activity of Chk.

V-11-0711 HCl

V-11-0711 HCl

Purity: 100%
Catalog No. T29083LAlias V-11-0711 HCl(1428339-47-2 Free base)
V-11-0711 HCl is a selective and highly effective choline kinase α (ChoKα) inhibitor that inhibits the catalytic activity of Chk.
Pack SizePriceAvailabilityQuantity
1 mg$213In Stock
5 mg$723In Stock
10 mg$1,130In Stock
25 mg$1,690In Stock
50 mg$2,280In Stock
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Purity:100%
ee:98.02%
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Product Introduction

Bioactivity
Description
V-11-0711 HCl is a selective and highly effective choline kinase α (ChoKα) inhibitor that inhibits the catalytic activity of Chk.
Targets&IC50
ChoKβ:220 nM, ChoKα:20 nM
In vitro
V-11-0711 inhibited recombinant human ChoKα with an IC50 of 20 nM, and showed 11 fold less activity against ChoKβ (IC50 220 nM). [1]
AliasV-11-0711 HCl(1428339-47-2 Free base)
Chemical Properties
Molecular Weight458.03
FormulaC27H36ClNO3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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